Results 11 to 20 of about 2,739,853 (293)

Mutagenic Studies of Folic Acid Antagonists [PDF]

open access: yesAntimicrobial Agents and Chemotherapy, 1977
Compounds that compete with folic acid (folic acid antagonists [FAAs]) become limited in their usefulness in the treatment of leukemia, malaria, and bacterial infections by the rapid development of resistance. Assays of the plasma levels of certain of these FAAs led to the observation, in about 25% of the determinations, that a higher ...
C. Genther   +3 more
semanticscholar   +3 more sources

Maternal exposure to folic acid antagonists and placenta-mediated adverse pregnancy outcomes. [PDF]

open access: yesCMAJ, 2008
Background: In previous studies, maternal exposure to folic acid antagonists was associated with increased risks of neural tube defects, cardiovascular defects, oral clefts and urinary tract defects.
Wen SW   +5 more
europepmc   +2 more sources

Thermal cooking and effects on folic acid content : A study of folic acid-enriched egg, asparagus and spinach [PDF]

open access: yes, 2022
application/pdfAA11325308-20220220-57In this study, we investigated the change in folic acid contents in foods during thermal cooking. The results showed that the folic acid content of boiled beaten eggs was significantly lower than that of raw, boiled ...
80340769   +31 more
core   +1 more source

Preconceptional folic acid supplement use in Lebanon. [PDF]

open access: yes, 2008
OBJECTIVE: The objective of the present study was to assess the prevalence and determinants of preconceptional folic acid supplement use among pregnant women in Lebanon. DESIGN/SETTING/SUBJECTS: The study was a descriptive epidemiological study. Analysis
Atoui, M   +15 more
core   +1 more source

Pilot Study on the Influence of Nutritional Counselling and Implant Therapy on the Nutritional Status in Dentally Compromised Patients. [PDF]

open access: yesPLoS ONE, 2016
OBJECTIVES:To investigate the impact of implant-prosthetic rehabilitation combined with nutritional counseling on the nutritional status of patients with severely reduced dentitions.
Bernd Wöstmann   +3 more
doaj   +1 more source

Caracterización bioquímica de la enzima bifuncional dihidrofolato reductasa-timidilato sintasa de Leishmania (Viannia) y su evaluación como blanco molecular

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2013
Introducción. La dihidrofolato reductasa (DHFR) se ha utilizado como blanco molecular en tratamientos antibacterianos, anticancerígenos y antipalúdicos.
Edison Osorio   +4 more
doaj   +1 more source

Histopathological effects of Methotrexate in mice livers [PDF]

open access: yesKirkuk Journal of Science, 2014
Background:Methotrexate is a folic acid antagonists that inhibits dihydrofolate reductase, resulting in a block in the synthesis of thymidine and inhibition of DNA synthesis. Methotrexate has been used for the treatment of malignancy, rheumatic disorders,
Asal A. Tawfeeq Sundus M. Taifoor
doaj   +1 more source

Folate catabolites in spot urine as non-invasive biomarkers of folate status during habitual intake and folic acid supplementation. [PDF]

open access: yes, 2013
Folate status, as reflected by red blood cell (RCF) and plasma folates (PF), is related to health and disease risk. Folate degradation products para-aminobenzoylglutamate (pABG) and para-acetamidobenzoylglutamate (apABG) in 24 hour urine have recently ...
Berthold Koletzko (144194)   +36 more
core   +2 more sources

Folic Acid Enhances Early Functional Recovery in a Piglet Model of Pediatric Head Injury [PDF]

open access: yes, 2010
For stroke and spinal cord injury, folic acid supplementation has been shown to enhance neurodevelopment and to provide neuroprotection. We hypothesized that folic acid would reduce brain injury and improve neurological outcome in a neonatal piglet model
Jill Ralston   +13 more
core   +1 more source

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