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Psychodermatology of the Female: Hormones, Skin and Mental Health Across the Lifespan

JEADV Clinical Practice, EarlyView.
Hormonal transitions across the female lifespan shape skin disease and psychiatric comorbidity through the brain–skin axis and Neuro‐Immuno‐Cutaneous‐Endocrine (NICE) network. This narrative review links puberty, menstruation, pregnancy, postpartum and menopause to dermatologic and psychosocial outcomes.
Sheila Sharifi, Jessica Gulati, Veranca Shah, Keira Barr, Mohammad Jafferany   +4 more
wiley   +1 more source

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Revealing T follicular helper cells with BCL6

Nature Reviews Immunology, 2021
Shane Crotty discusses three independent studies published in 2009 that characterized T follicular helper cells as a distinct subset of CD4+ T cells on the basis of selective expression of BCL6.
Shane Crotty
openaire   +4 more sources

T follicular helper cells and T follicular regulatory cells in rheumatic diseases

Nature Reviews Rheumatology, 2019
As a hallmark of autoimmune rheumatic diseases, autoantibodies have been used in diagnosis for decades. However, the immunological mechanism underlying their generation has only become clear following the identification of T follicular helper (TFH) cells and T follicular regulatory (TFR) cells. TFH cells are instrumental in supporting antibody affinity
Jun Deng, Yunbo Wei, Válter R. Fonseca, Luis Graca, Di Yu   +4 more
openaire   +5 more sources

T follicular helper cells in space-time

Nature Reviews Immunology, 2016
T follicular helper (TFH) cells play a crucial part in the development of humoral immunity by controlling the formation of, and the cellular reactions that occur in, germinal centres. Within these organized lymphoid tissue microstructures, B cells proliferate and somatically mutate to produce long-lived, high-affinity plasma cells and memory B cells ...
Hai Qi
openaire   +4 more sources

Follicular T helper cells and cutaneous T-cell lymphomas

British Journal of Dermatology, 2022
Abstract Linked Article:  Wang et al. Br J Dermatol 2022; 187:970–980.
openaire   +2 more sources

SOSTDC1-producing follicular helper T cells promote regulatory follicular T cell differentiation

Science, 2020
SOSTDC1 for germinal center regulation T follicular helper (T FH ) cells are CD4 + T cells that facilitate B cell antibody production and B cell memory responses in the germinal centers (GCs) of lymphoid organs. These activities are in turn restrained by T follicular regulatory (T
Xin Wu, Yun Wang, Rui Huang, Qujing Gai, Haofei Liu, Meimei Shi, Xiang Zhang, Yonglin Zuo, Longjuan Chen, Qiwen Zhao, Yu Shi, Fengchao Wang, Xiaowei Yan, Huiping Lu, Senlin Xu, Xiaohong Yao, Lin Chen, Xia Zhang, Qiang Tian, Ziyan Yang, Bo Zhong, Chen Dong, Yan Wang, Xiu-Wu Bian, Xindong Liu   +24 more
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T follicular helper cells in autoimmune diseases

Journal of Autoimmunity, 2023
T follicular helper (Tfh) cells with the phenotype of mainly expressing surface molecules C-X-C motif chemokine receptor type 5 (CXCR5), inducible co-stimulator (ICOS), secreting cytokine interleukin-21 (IL-21) and requiring the transcription factor B cell lymphoma 6 (BCL-6) have been recently defined as a new subset of CD4+ T cells.
Xindi Wei, Xiaoyin Niu
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T Follicular Helper Cell Differentiation

Science, 2009
When B cells respond to an infection, they often require help from CD4+ T cells to mount a proper response. It is thought that a subset of CD4+ effector T cells, called T follicular helper cells (TFH), performs this function. Several subsets of effector CD4+ T cells arise, depending on the type of infection, which have distinct transcriptional programs
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Follicular helper T cells in rheumatoid arthritis

Clinical Rheumatology, 2015
Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation in the joints and other tissues. Rheumatoid factor (RF) and anticyclic citrullinated peptides (anti-CCP) are biomarkers for the evaluation of RA although their functions in the pathogenesis of RA are poorly understood.
Meixing, Yu, Vanesssa, Cavero, Qiao, Lu, Hong, Li   +3 more
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Follicular Helper CD4 T Cells (T_FH)

Annual Review of Immunology, 2011
T cell help to B cells is a fundamental aspect of adaptive immunity and the generation of immunological memory. Follicular helper CD4 T (TFH) cells are the specialized providers of B cell help. TFHcells depend on expression of the master regulator transcription factor Bcl6.
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