Results 101 to 110 of about 19,954 (207)

Extracellular Vesicle‐Derived microRNAs as Fluid Biomarkers in Neurodegenerative Diseases: A Systematic Review

open access: yesJournal of Neurochemistry, Volume 170, Issue 1, January 2026.
Given the absence of curative treatments for neurodegenerative diseases, early detection and therapeutic intervention are critical to slowing disease progression. The last decade has seen accumulating evidence for microRNA dysregulation in circulating extracellular vesicles (EVs); however, assessing reproducibility between studies remains challenging ...
Aliyah Zaman   +2 more
wiley   +1 more source

A counter gradient of Activin A and follistatin instructs the timing of hair cell differentiation in the murine cochlea

open access: yeseLife, 2019
The mammalian auditory sensory epithelium has one of the most stereotyped cellular patterns known in vertebrates. Mechano-sensory hair cells are arranged in precise rows, with one row of inner and three rows of outer hair cells spanning the length of the
Meenakshi Prajapati-DiNubila   +4 more
doaj   +1 more source

Adipose Mesenchymal Stem Cells Promote Wound Healing by Modulating Expression of SERPINE1 in Dermal Fibroblasts and Keratinocytes

open access: yesStem Cells International, Volume 2026, Issue 1, 2026.
Background Adipose‐derived mesenchymal stem cells (ADSCs) have great potential in the realm of tissue repair and regenerative medicine. However, the exact effects of ADSCs on the healing of skin wounds and the underlying mechanisms remain unexplored. Here, we investigated the effects of ADSCs on fibroblasts and keratinocytes and their related molecular
YeHua Liang   +6 more
wiley   +1 more source

Osmotically Tunable Microdroplets Enable Amplification‐Free CRISPR Detection of Gene Doping

open access: yesAdvanced Science, Volume 12, Issue 48, December 29, 2025.
A novel amplification‐free clustered regularly interspaced short palindromic repeats/CRISPR‐associated protein (CRISPR/Cas) 12a assay is integrated with osmotically shrinkable double emulsion droplets for the rapid and ultrasensitive detection of gene doping.
Jihun Han   +6 more
wiley   +1 more source

HDAC4 regulates skeletal muscle regeneration via soluble factors [PDF]

open access: yes, 2018
Skeletal muscle possesses a high ability to regenerate after an insult or in pathological conditions, relying on satellite cells, the skeletal muscle stem cells.
Alessandra Renzini   +5 more
core   +3 more sources

Activin A: its role and involvement in inflammatory diseases [PDF]

open access: yes, 2015
Activin proteins are members of the transforming growth factor-β family. Activin A is involved in several biological responses including wound repair, cell death, proliferation and differentiation of many cell types.
Basir, Rusliza   +4 more
core  

High-throughput analysis of the RNA-induced silencing complex in myotonic dystrophy type 1 patients identifies the dysregulation of miR-29c and its target ASB2 [PDF]

open access: yes, 2018
Myotonic dystrophy type 1 (DM1) is a multi-systemic disorder caused by abnormally expanded stretches of CTG DNA triplets in the DMPK gene, leading to mutated-transcript RNA-toxicity.
Cappella, Marisa   +11 more
core   +2 more sources

Follistatin and the Breast Implant Capsule

open access: yesPlastic and Reconstructive Surgery - Global Open, 2017
Background: Breast capsular contracture remains an elusive problem faced by plastic surgeons and is the leading long-term complication after breast implantation. Follistatin (Fst) is a protein with known anti-inflammatory and antifibrotic properties and has the potential to limit the severity of diseases associated with ...
Frenkiel, Brett A.   +3 more
openaire   +2 more sources

Follistatin, a Novel Biomarker for Malignant Gliomas [PDF]

open access: yes, 2015
Molecular biomarkers are commonly used for the management of several types of malignant tumours in routine clinical practice. However, this is not the case for malignant gliomas.
Abel, Peter   +7 more
core   +2 more sources

Activin/Follistatin and Atherosclerosis-A Review-

open access: yesJournal of Atherosclerosis and Thrombosis, 1998
Activin-A, a member of the TGF-beta superfamily, has a variety of important biological functions. Concerning Møs, we demonstrated that MSR which has a key role in disposing of modified LDL is downregulated by activin-A. This leads to a decrease in binding, cell association, and degradation of Ac-LDL, resulting in the inhibition of foam cell formation ...
K, Kozaki, Y, Ouchi
openaire   +3 more sources

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