Results 101 to 110 of about 19,656 (205)

Stem Cell Secretome Treatment Reduces Adiposity and Improves Glucose Handling During Obesity and Weight Loss in Mice

Obesity, Volume 34, Issue 2, Page 382-393, February 2026.
ABSTRACT Objective In this study, we investigated the effects of a stem cell‐derived secretome product on adiposity and tissue quality and insulin and glucose levels in obese mice and those undergoing dietary weight loss. Methods Following 16 weeks of high fat diet mice received acute (4 weeks) biweekly intramuscular injections with vehicle or ...
Zachary J. Fennel, Anu S. Kurian, Paul‐Emile Bourrant, Chad M. Skiles, Robert J. Castro, Elena M. Yee, Scott A. Greilach, Hans S. Keirstead, Gabriel Nistor, Nicole C. Berchtold, Thomas E. Lane, Micah J. Drummond   +11 more
wiley   +1 more source

Frequently Reported Blood Biomarkers in Sarcopenia Clinical Trials: A Systematic Review and Meta‐Analysis

Aging Cell, Volume 25, Issue 2, February 2026.
This systematic review and meta‐analysis identifies blood‐based biomarkers (BBMs) reported in sarcopenia trials, investigating the impact of sarcopenia interventions on BBMs concentrations. Significant heterogeneity was observed in sarcopenia outcomes. Interventions had a limited impact on BBMs, except for IGF‐1, which was significantly impacted by the
Emma Calluy, Yveline Malrechauffé, Emma Boretti, Sophie Van Heden, Dolores Sanchez‐Rodriguez, Yoke Mun Chan, Etienne Cavalier, Aurélie Ladang, Jean‐Yves Reginster, Jonathan Douxfils, Charlotte Beaudart   +10 more
wiley   +1 more source

Activin A: its role and involvement in inflammatory diseases [PDF]

, 2015
Activin proteins are members of the transforming growth factor-β family. Activin A is involved in several biological responses including wound repair, cell death, proliferation and differentiation of many cell types.
Basir, Rusliza, Chuah, Yaw Kuang, Nordin, Norshariza, Talib, Herni, Tie, Tung Hing   +4 more
core  

The bone morphogenetic protein axis is a positive regulator of skeletal muscle mass [PDF]

, 2013
Although the canonical transforming growth factor β signaling pathway represses skeletal muscle growth and promotes muscle wasting, a role in muscle for the parallel bone morphogenetic protein (BMP) signaling pathway has not been defined. We report,
Amthor, Amthor, Ball, Bayat, Bianca C. Bernardo, Bodine, Bogdanovich, Bradley J. Turner, Catherine E. Winbanks, Chung, Claudia Beyer, Clever, Cohen, Craig A. Harrison, Donaldson, Dworkin, Dworkin, Fischle, Gregorevic, Grönroos, Gurney, Hayashi, Heitman, Holley, Hongwei Qian, Ibebunjo, Imamura, Ishida, Julie R. McMullen, Justin L. Chen, Kalista, Kambadur, Katagiri, Kevin I. Watt, Langenfeld, Lars Larsson, Latres, Lee, Lee, Lee, Massagué, Mathews, McCabe, McPherron, Moresi, Musarò, Nakao, Nickel, Ochala, Paul Gregorevic, Pescatori, Potthoff, Pourquié, Rachel E. Thomson, Rafael, Rebbapragada, Rommel, Ruschke, Sako, Sandri, Sartori, Sartori, Sean L. McGee, Shioi, Stitt, Suryawan, Tang, Timothy Connor, Townsend, Trendelenburg, Winbanks, Winbanks, Yamamoto, Yingying Liu, Zhou, Zimmerman   +75 more
core   +2 more sources

Profiling of Extracellular Vesicles of Non‐Small Cell Lung Cancer Reveals Proteins Associated With Osimertinib Resistance

Journal of Extracellular Vesicles, Volume 15, Issue 1, January 2026.
Non‐invasive biomarkers are needed to further personalize EGFR tyrosine kinase inhibitor (EGFR TKI) osimertinib treatment in non‐small cell lung cancer (NSCLC) patients. By analysing the proteome of extracellular vesicles (EVs) isolated from an osimertinib resistant NSCLC cell line and from serum of patients given osimertinib in second line within the ...
Albano Cáceres‐Verschae, Petra Hååg, Sofia Joelsson, Per Hydbring, Bo Franzén, Ákos Végvári, Inger Johanne Z. Eide, Nupur Agarwal, Siddharth Sourabh Sahu, Fredrik Stridfeldt, Luigi De Petris, Apurba Dev, Simon Ekman, Odd Terje Brustugun, Rolf Lewensohn, Kristina Viktorsson   +15 more
wiley   +1 more source

High circulating activin A level is associated with tumor progression and predicts poor prognosis in lung adenocarcinoma [PDF]

, 2016
Activin A (ActA)/follistatin (FST) signaling has been shown to be deregulated in different tumor types including lung adenocarcinoma (LADC). Here, we report that serum ActA protein levels are significantly elevated in LADC patients (n=64) as compared ...
Alzheimer, Andl, Beer, Beer, Blackhall, Bracke, Brusselle, Cho, Coletta, Coletta, Coletta, Cui, Diamandis, Diamandis, Dome, Domont, Garay, Goodglick, Harrison, Hedger, Hill, Johansen, Kaplan, Kern, Kouroumalis, Leto, Leto, Li, Ling, Massague, Miao, Miyamoto, Mori, O'Hehir, Patz, Pauwels, Petraglia, Petzelbauer, Plomgaard, Regnard, Rimokh, Rini, Roncalli, Schneyer, Schulte-Hermann, Shainkin-Kestenbaum, Skarin, Sone, Stieber, Taguchi, Ueno, Vale, Viladiu, Woodruff, Wu, Xu, Yamamoto, Zhang, Zhang   +58 more
core   +1 more source

TLR3 Deficiency Leads to a Dysregulation in the Global Gene-Expression Profile in Murine Oviduct Epithelial Cells Infected with Chlamydia muridarum [PDF]

, 2019
OBJECTIVE Describe the implementation and effects of Mobile Acute Care for Elders (MACE) consultation at a Veterans Affairs Medical Center (VAMC). DESIGN Retrospective cohort analysis.
Derbigny, Wilbert A, Kumar, Ramesh
core   +2 more sources

Follistatin and the Breast Implant Capsule

Plastic and Reconstructive Surgery - Global Open, 2017
Background: Breast capsular contracture remains an elusive problem faced by plastic surgeons and is the leading long-term complication after breast implantation. Follistatin (Fst) is a protein with known anti-inflammatory and antifibrotic properties and has the potential to limit the severity of diseases associated with ...
Frenkiel, Brett A., Temple-Smith, Peter, de Kretser, David, Southwick, Graeme J.   +3 more
openaire   +2 more sources

Follistatin-like 5 is expressed in restricted areas of the adult mouse brain: Implications for its function in the olfactory system [PDF]

, 2014
Follistatin‐like 5 (Fstl5), a member of the follistatin family of genes, encodes a secretory glycoprotein. Previous studies revealed that other members of this family including Fstl1 and Fstl3 play an essential role in development, homeostasis, and ...
Masuda Tomoyuki, Nagaoka Atsuko, Nagase Takahiro, Sakuma Chie, Ueda Shuichi, Yaginuma Hiroyuki, Yamagishi Toshiyuki, 増田 知之   +7 more
core   +2 more sources

Activin/Follistatin and Atherosclerosis-A Review-

Journal of Atherosclerosis and Thrombosis, 1998
Activin-A, a member of the TGF-beta superfamily, has a variety of important biological functions. Concerning Møs, we demonstrated that MSR which has a key role in disposing of modified LDL is downregulated by activin-A. This leads to a decrease in binding, cell association, and degradation of Ac-LDL, resulting in the inhibition of foam cell formation ...
K, Kozaki, Y, Ouchi
openaire   +3 more sources