Systemic activation of activin A signaling causes chronic kidney disease-mineral bone disorder [PDF]
The high cardiovascular mortality associated with chronic kidney disease (CKD) is caused in part by the CKD-mineral bone disorder (CKD-MBD) syndrome.
Sugatani, Toshifumi
core +2 more sources
Analysis of Oct4-dependent transcriptional networks regulating self-renewal and pluripotency in human embryonic stem cells [PDF]
The POU domain transcription factor OCT4 is a key regulator of pluripotency in the early mammalian embryo and is highly expressed in the inner cell mass of the blastocyst. Consistent with its essential role in maintaining pluripotency, Oct4 expression is
Adjaye, J. +8 more
core +2 more sources
Background Sheng-ji Hua-yu(SJHY) formula is one of the most useful Traditional Chinese medicine (TCM) in the treatment of the delayed diabetic wound.
Le Kuai +12 more
doaj +1 more source
Differential expression of follistatin and FLRG in human breast proliferative disorders
Background Activins are growth factors acting on cell growth and differentiation. Activins are expressed in high grade breast tumors and they display an antiproliferative effect inducing G0/G1 cell cycle arrest in breast cancer cell lines.
Amaral Vania F +11 more
doaj +1 more source
Background and objectives: Nonalcoholic fatty liver disease (NAFLD) is a chronic hepatic disease characterized by fat accumulation inside hepatocytes. The aim of this study was to evaluate effects of exercise training and resveratrol supplementation on ...
alireza barari +3 more
doaj
The role of Follistatin-like 3 (Fstl3) in cardiac hypertrophy and remodelling
Follistatins are extracellular inhibitors of TGF-β family ligands like activin A, myostatin and bone morphogenetic proteins. Follistatin-like 3 (Fstl3) is a potent inhibitor of activin signalling and antagonises the cardioprotective role of activin A in ...
Panse, Kalyani, Panse, Kalyani
core +1 more source
The effect of two different intensities resistance training on muscle growth regulatory myokines in sedentary young women [PDF]
Background: The aim of this study was to investigate the effect of resistance training with different intensities on serum myostatin and follistatin levels in sedentary young women. Materials and Methods: In this practical and semi experimental study,
Seyyed Reza Attarzadeh Hosseini +2 more
doaj
Effects of weight loss rate on myostatin and follistatin dynamics in patients with obesity
BackgroundExercise-induced cytokines involved in controlling body composition include myostatin (MST) and follistatin (FST), both of which are influenced by physical activity.
Satoshi Kurose +4 more
doaj +1 more source
The Reign of Follistatin in Tumors and Their Microenvironment: Implications for Drug Resistance
Follistatin (FST) is a potent neutralizer of the transforming growth factor-β superfamily and is associated with normal cellular programs and various hallmarks of cancer, such as proliferation, migration, angiogenesis, and immune evasion.
Jennifer Sosa +2 more
doaj +1 more source
Abstracts of the 18th SCWD Conference, 11‐13 December 2025 in Rome/Italy
JCSM Communications, Volume 9, Issue 1, January/June 2026.
wiley +1 more source

