Results 181 to 190 of about 19,954 (207)
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Follistatin

The International Journal of Biochemistry & Cell Biology, 1998
Follistatin, a secreted protein is able to bind and neutralise the actions of many members of the Transforming Growth Factor-beta family of proteins. Follistatin was first implicated in the regulation of follicle-stimulating hormone secretion in the pituitary and subsequently in other regions of the adult body associated with reproductive functions ...
Tak W. Mak   +4 more
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Differential actions of follistatin and follistatin-like 3

Molecular and Cellular Endocrinology, 2004
Follistatin (FS) is an important physiological regulator of activin and other TGFbeta superfamily members. The recently discovered follistatin-like 3 (FSTL3; a.k.a. FLRG; FSRP) shares significant structural and functional homology with FS, but also has some interesting differences, including a prominent nuclear localization.
Alan, Schneyer   +6 more
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Follistatin-related protein (FSRP): a new member of the follistatin gene family

Molecular and Cellular Endocrinology, 2001
The identification and characterization of follistatin related protein (FSRP) suggests that the follistatin (FS) gene family may actually contain two sub-families. The first includes FS and FSRP by virtue of their high degree of structural homology and comparable activin-binding activity, while the second sub-family contains extracellular matrix ...
A, Schneyer   +5 more
openaire   +2 more sources

Follistatin: A Multifunctional Regulatory Protein

Frontiers in Neuroendocrinology, 1998
Follistatin was first described in 1987 as a follicle-stimulating hormone inhibiting substance present in ovarian follicular fluid. We now know that this effect of follistatin is only one of its many properties in a number of reproductive and nonreproductive systems.
D J, Phillips, D M, de Kretser
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Inhibins, activins and follistatins

Journal of Steroid Biochemistry, 1989
Inhibins are proteins consisting of two subunits, 18 K alpha- and 14 K beta-subunits, linked by disulfide bonds. Two forms of inhibins A and B consisting of a common alpha-subunit and a similar but distinguishable beta-subunit specifically suppress the secretion and cell content of FSH in a delayed action.
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Follistatin/activin-binding protein

Trends in Endocrinology & Metabolism, 1992
Follistatin, or follicle-stimulating hormone (FSH) suppressing protein, is a protein isolated from side fractions in the purification of inhibin and activin, which shares with inhibin the property of suppressing the secretion of FSH from the pituitary gonadotroph. This protein is structurally distinct from inhibin.
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Expression patterns of follistatin and two follistatin-related proteins during mouse development. [PDF]

open access: possibleThe International journal of developmental biology, 2000
Contains fulltext : 308963.pdf (Publisher’s version ) (Closed access)
Groot, E. de   +6 more
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Deranged expression of follistatin and follistatin-like protein in women with ovarian endometriosis

Fertility and Sterility, 2007
To evaluate the messenger RNA (mRNA) expression and peptide localization of follistatin and follistatin-like protein (FLRG) in ovarian endometriosis, compared to healthy human endometrium.Samples of ovarian endometriotic and healthy endometrial tissues were processed by semiquantitative reverse transcriptase-polymerase chain reaction and ...
Torres, Paulo B.   +5 more
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Follistatin‐like 1 in vertebrate development

Birth Defects Research Part C: Embryo Today: Reviews, 2013
Follistatin‐like 1 (Fstl1) is a member of the secreted protein acidic rich in cysteins (SPARC) family and has been implicated in many different signaling pathways, including bone morphogenetic protein (BMP) signaling. In many different developmental processes like, dorso‐ventral axis establishment, skeletal, lung and ureter development, loss of ...
M, Sylva   +2 more
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Site-specific mutagenesis of human follistatin

Biochemical and Biophysical Research Communications, 1991
Follistatin is a monomeric protein originally discovered in ovarian follicular fluid as a suppressor of pituitary follicle-stimulating hormone (FSH) secretion, and later identified as a binding protein for activin. To explore the role of the Asn-linked carbohydrate chains on the follistatin molecule in regard to the inhibition of FSH secretion and ...
S, Inouye, Y, Guo, N, Ling, S, Shimasaki
openaire   +2 more sources

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