Results 181 to 190 of about 19,656 (205)

Follistatin-related protein (FSRP): a new member of the follistatin gene family

Molecular and Cellular Endocrinology, 2001
The identification and characterization of follistatin related protein (FSRP) suggests that the follistatin (FS) gene family may actually contain two sub-families. The first includes FS and FSRP by virtue of their high degree of structural homology and comparable activin-binding activity, while the second sub-family contains extracellular matrix ...
A, Schneyer, D, Tortoriello, Y, Sidis, H, Keutmann, T, Matsuzaki, W, Holmes   +5 more
openaire   +2 more sources

Follistatin: A Multifunctional Regulatory Protein

Frontiers in Neuroendocrinology, 1998
Follistatin was first described in 1987 as a follicle-stimulating hormone inhibiting substance present in ovarian follicular fluid. We now know that this effect of follistatin is only one of its many properties in a number of reproductive and nonreproductive systems.
D J, Phillips, D M, de Kretser
openaire   +2 more sources

Inhibins, activins and follistatins

Journal of Steroid Biochemistry, 1989
Inhibins are proteins consisting of two subunits, 18 K alpha- and 14 K beta-subunits, linked by disulfide bonds. Two forms of inhibins A and B consisting of a common alpha-subunit and a similar but distinguishable beta-subunit specifically suppress the secretion and cell content of FSH in a delayed action.
openaire   +2 more sources

Follistatin/activin-binding protein

Trends in Endocrinology & Metabolism, 1992
Follistatin, or follicle-stimulating hormone (FSH) suppressing protein, is a protein isolated from side fractions in the purification of inhibin and activin, which shares with inhibin the property of suppressing the secretion of FSH from the pituitary gonadotroph. This protein is structurally distinct from inhibin.
openaire   +2 more sources

Expression patterns of follistatin and two follistatin-related proteins during mouse development. [PDF]

The International journal of developmental biology, 2000
Contains fulltext : 308963.pdf (Publisher’s version ) (Closed access)
Groot, E. de, Feijen, A., Eib, D.W., Zwijsen, A., Sugino, H., Martens, G.J.M., Eijnden-van Raaij, A.J.M. van den   +6 more
openaire   +2 more sources

Deranged expression of follistatin and follistatin-like protein in women with ovarian endometriosis

Fertility and Sterility, 2007
To evaluate the messenger RNA (mRNA) expression and peptide localization of follistatin and follistatin-like protein (FLRG) in ovarian endometriosis, compared to healthy human endometrium.Samples of ovarian endometriotic and healthy endometrial tissues were processed by semiquantitative reverse transcriptase-polymerase chain reaction and ...
Torres, Paulo B., Florio, Pasquale, Ferreira, Marcia C., Torricelli, Michela, Reis, Fernando M., Petraglia, Felice   +5 more
openaire   +5 more sources

Follistatin‐like 1 in vertebrate development

Birth Defects Research Part C: Embryo Today: Reviews, 2013
Follistatin‐like 1 (Fstl1) is a member of the secreted protein acidic rich in cysteins (SPARC) family and has been implicated in many different signaling pathways, including bone morphogenetic protein (BMP) signaling. In many different developmental processes like, dorso‐ventral axis establishment, skeletal, lung and ureter development, loss of ...
M, Sylva, A F M, Moorman, M J B, van den Hoff   +2 more
openaire   +2 more sources

Site-specific mutagenesis of human follistatin

Biochemical and Biophysical Research Communications, 1991
Follistatin is a monomeric protein originally discovered in ovarian follicular fluid as a suppressor of pituitary follicle-stimulating hormone (FSH) secretion, and later identified as a binding protein for activin. To explore the role of the Asn-linked carbohydrate chains on the follistatin molecule in regard to the inhibition of FSH secretion and ...
S, Inouye, Y, Guo, N, Ling, S, Shimasaki
openaire   +2 more sources

[Ovine Follistatin gene expression and functional analysis of follistatin domains].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology, 2011
In order to study ovine follistatin function, we amplified the total of 1038 base pair of ovine complete follistatin cDNA and cloned into pGEM-T vector by RT-PCR from ovine ovary RNA. After removal of the signal peptide it was subcloned into the pET41a to construct the prokaryotic expression vector, named pFSsig-.
Ning, Zhang, Xuemei, Zhang, Mingjun, Liu, Lixin, Tan   +3 more
openaire   +1 more source

Porcine follistatin gene structure supports two forms of mature follistatin produced by alternative splicing

Biochemical and Biophysical Research Communications, 1988
Follistatin (FS), a novel gonadal protein which inhibits specifically the secretion of pituitary follicle stimulating hormone (FSH), has recently been isolated from porcine follicular fluid. cDNA cloning of the porcine ovarian FS precursor revealed two populations of cDNAs which differed at the 3'-region of the open reading frames; one population ...
S, Shimasaki, M, Koga, F, Esch, M, Mercado, K, Cooksey, A, Koba, N, Ling   +6 more
openaire   +2 more sources