Results 41 to 50 of about 102,953 (306)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Water Resources of the Fond du Lac Indian Reservation, East-Central Minnesota [PDF]
Saint Paul, MN: USGS.This interesting report presents the findings of a hydrologic study of the Fond du Lac Indian Reservation. The study is the outcome of a 1978 Federal mandate to the Bureau of Indian Affairs to review Indian water-rights claims in ...
Ruhl, James F +1 more
core
Shared neoantigens’ atlas for off-the-shelf cancer vaccine development
Background We have recently described that the most prevalent 100 mutations identified in human cancers, both single nucleotide variations (SNVs) and InDels, generate a handful number of shared mutated neoantigens (SNV and InDel-NeoAgs) in association ...
Angela Mauriello +4 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Fond du Lac Resource Management: 2008 Integrated Resource Management Plan [PDF]
This very comprehensive document was reviewed and is felt to have significant content and analysis relevant to Minnesota’s coastal area and water resources.
Fond du Lac Band of Lake Superior Chippewa
core
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
A collaborative project between Philippa Wood and Angie Butler of ABPress. Fond Farewells is a pair of limited edition artists' books which form part of an on-going project called Endangered Species, this particular edition examines lost language.
Philippa Wood (17170330) +1 more
core +1 more source
Savremeno naoružanje i vojna oprema za broj 1/2014
Star ali modernizovanIz prodavnice na liniju frontaOklopna štednjaPoljski PL-01 koncept borbeno voziloRusija planira formiranje 40 novih brigada do 2020 godineJapan razvija radar dugog dometa za otkrivanje stelt letelicaTurska odabrala kineski raketni ...
Dragan M. Vučković
doaj +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source

