Results 1 to 10 of about 1,746 (120)

Prediction of itraconazole minimum inhibitory concentration for Fonsecaea pedrosoi using Fourier Transform Infrared Spectroscopy (FTIR) and chemometrics. [PDF]

PLoS ONE, 2020
Fonsecaea pedrosoi is one of the main agents of chromoblastomycosis, a chronic subcutaneous mycosis. Itraconazole (ITC) is the most used antifungal in its treatment, however, in vitro antifungal susceptibility tests are important to define the best ...
Alessandra Koehler, Valeriano Antonio Corbellini, Daiane Heidrich, Maria Lúcia Scroferneker   +3 more
doaj   +4 more sources

Melanin in Fonsecaea pedrosoi: a trap for oxidative radicals [PDF]

BMC Microbiology, 2010
Background The pathogenic fungus Fonsecaea pedrosoi constitutively produces the pigment melanin, an important virulence factor in fungi. Melanin is incorporated in the cell wall structure and provides chemical and physical protection for the fungus.
de Souza Wanderley, Borba Luana P, Vugman Ney V, Herbst Marcelo H, Seabra Sergio H, Franzen Anderson J, Cunha Marcel ML, Rozental Sonia   +7 more
doaj   +7 more sources

Silver(I) 1,10-Phenanthroline Complexes Are Active against Fonsecaea pedrosoi Viability and Negatively Modulate Its Potential Virulence Attributes [PDF]

Journal of Fungi, 2023
The genus Fonsecaea is one of the etiological agents of chromoblastomycosis (CBM), a chronic subcutaneous disease that is difficult to treat. This work aimed to evaluate the effects of copper(II), manganese(II) and silver(I) complexes coordinated with 1 ...
Ingrid S. Sousa, Tatiana D. P. Vieira, Rubem F. S. Menna-Barreto, Allan J. Guimarães, Pauraic McCarron, Malachy McCann, Michael Devereux, André L. S. Santos, Lucimar F. Kneipp   +8 more
doaj   +2 more sources

Establishment of epidemiological cutoff values for Fonsecaea pedrosoi, the primary etiologic agent of chromoblastomycosis, and eight antifungal medications [PDF]

Journal of Clinical Microbiology
Chromoblastomycosis, a fungal neglected tropical disease, is acquired through traumatic inoculation and is clinically characterized by a chronic granulomatous infection of the skin and subcutaneous tissue. Fonsecaea pedrosoi is the most commonly reported
Dallas J. Smith, Marcia S. C. Melhem, Jessy Dirven, Conceição Maria Pedrozo e Silva de Azevedo, Sirlei Garcia Marques, Bruna Jacomel Favoreto de Souza Lima, Vania Aparecida Vicente, Maria da Glória Teixeira Sousa, James Venturini, Nathan P. Wiederhold, Amir Seyedmousavi, Philippe J. Dufresne, Sybren de Hoog, Shawn R. Lockhart, Ferry Hagen, Daniel Wagner de C. L. Santos   +15 more
doaj   +2 more sources

Expanding the Toolbox for Functional Genomics in Fonsecaea pedrosoi: The Use of Split-Marker and Biolistic Transformation for Inactivation of Tryptophan Synthase (trpB) Gene [PDF]

Journal of Fungi, 2023
Chromoblastomycosis (CBM) is a disease caused by several dematiaceous fungi from different genera, and Fonsecaea is the most common which has been clinically isolated.
Luísa Dan Favilla, Tatiana Sobianski Herman, Camila da Silva Goersch, Rosangela Vieira de Andrade, Maria Sueli Soares Felipe, Anamélia Lorenzetti Bocca, Larissa Fernandes   +6 more
doaj   +2 more sources

Study of tissue inflammatory response in different mice strains infected by dematiaceous fungi Fonsecaea pedrosoi [PDF]

Anais Brasileiros de Dermatologia, 2019
: Background: Diseases caused by melanized fungi include mycetoma, chromoblastomycosis and phaeohyphomycosis. This broad clinical spectrum depends on the dynamic interactions between etiologic agent and host.
Marilia Marufuji Ogawa, Mario Mariano, Maria Regina Regis Silva, Milvia Maria Simões e Silva Enokihara, Nilceo Schwery Michalany, Angela Satie Nishikaku, Agenor Messias Silvestre, Jane Tomimori   +7 more
doaj   +2 more sources

Corneal Chromoblastomycosis Caused by Fonsecaea pedrosoi [PDF]

Case Reports in Ophthalmology, 2015
Purpose: To report 2 unusual cases of fungal keratitis due to Fonsecaea pedrosoi. Methods: Two patients were diagnosed with Fonsecaea pedrosoi keratitis. Their files were reviewed for predisposing factors, clinical characteristics, microbiological study,
Winai Chaidaroon, Napaporn Tananuvat, Pimploy Chavengsaksongkram, Nongnuch Vanittanakom   +3 more
doaj   +2 more sources

Melanin particles isolated from the fungus Fonsecaea pedrosoi activates the human complement system [PDF]

Memorias do Instituto Oswaldo Cruz, 2018
BACKGROUND Melanin production has been associated with virulence in various pathogenic fungi, including Fonsecaea pedrosoi, the major etiological agent for chromoblastomycosis, a subcutaneous fungal disease that occurs in South America.
Lysianne Pinto, Luiz Fernando Zmetek Granja, Mariana Amorim de Almeida, Daniela Sales Alviano, Maria Helena da Silva, Regina Ejzemberg, Sonia Rozental, Celuta Sales Alviano   +7 more
doaj   +2 more sources

Molecular Epidemiology of Fonsecaea Species [PDF]

Emerging Infectious Diseases, 2011
To assess population diversities among 81 strains of fungi in the genus Fonsecaea that had been identified down to species level, we applied amplified fragment-length polymorphism (AFLP) technology and sequenced the internal transcribed spacer regions ...
Mohammad Javad Najafzadeh, Jiufeng Sun, Vania A. Vicente, Corne H.W. Klaassen, Alexandro Bonifaz, A.H.G. Gerrits van den Ende, Steph B.J. Menken, G. Sybren de Hoog   +7 more
doaj   +5 more sources

Biofilm Formation by Chromoblastomycosis Fungi Fonsecaea pedrosoi and Phialophora verrucosa: Involvement with Antifungal Resistance [PDF]

Journal of Fungi, 2022
Patients with chromoblastomycosis (CBM) suffer chronic tissue lesions that are hard to treat. Considering that biofilm is the main growth lifestyle of several pathogens and it is involved with both virulence and resistance to antimicrobial drugs, we have
Ingrid S. Sousa, Thaís P. Mello, Elaine P. Pereira, Marcela Q. Granato, Celuta S. Alviano, André L. S. Santos, Lucimar F. Kneipp   +6 more
doaj   +2 more sources