Results 21 to 30 of about 1,548 (182)

In vitro susceptibility testing of Fonsecaea pedrosoi to antifungals [PDF]

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 1997
Based on the difficulties experienced in the treatment of chromoblastomycosis, 12 primary human isolates of F. pedrosoi, were tested for their in vitro susceptibility to various antimycotics. We adapted the recommendations of the NCCLS for yeasts and followed the indications for mold testing from other authors in order to determine their MIC’s and the ...
BEDOUT, Catalina de   +2 more
openaire   +5 more sources

Prediction of itraconazole minimum inhibitory concentration for Fonsecaea pedrosoi using Fourier Transform Infrared Spectroscopy (FTIR) and chemometrics. [PDF]

open access: yesPLoS ONE, 2020
Fonsecaea pedrosoi is one of the main agents of chromoblastomycosis, a chronic subcutaneous mycosis. Itraconazole (ITC) is the most used antifungal in its treatment, however, in vitro antifungal susceptibility tests are important to define the best ...
Alessandra Koehler   +3 more
doaj   +2 more sources

Phosphatase activity on the cell wall ofFonsecaeapedrosoi [PDF]

open access: yesMedical Mycology, 2003
The activity of a phosphatase was characterized in intact mycelial forms of Fonsecaea pedrosoi, a pathogenic fungus that causes chromoblastomycosis. At pH 5.5, this fungus hydrolyzed p-nitrophenylphosphate (p-NPP) to p-nitrophenol (p-NP) at a rate of 12.78 +/- 0.53 nmol p-NP per h per mg hyphal dry weight.
Kneipp, L. F.   +6 more
openaire   +4 more sources

Úlcera corneal por Fonsecaea pedrosoi, las dificultades del tratamiento de un germen desafiante: reporte de caso

open access: yesRevista Mexicana de Oftalmología, 2022
Introducción: Las queratitis micóticas son enfermedades agresivas, con secuelas que pueden llevar a discapacidad visual permanente. Objetivo: Describimos un caso de úlcera corneal por un agente infrecuente, Fonsecaea pedrosoi, resaltando el dificultoso ...
Claudia Martínez-Córdoba   +2 more
doaj   +2 more sources

HIV Aspartic Peptidase Inhibitors Modulate Surface Molecules and Enzyme Activities Involved with Physiopathological Events in Fonsecaea pedrosoi [PDF]

open access: yesFrontiers in Microbiology, 2017
Fonsecaea pedrosoi is the main etiological agent of chromoblastomycosis, a recalcitrant disease that is extremely difficult to treat. Therefore, new chemotherapeutics to combat this fungal infection are urgently needed.
Vanila F. Palmeira   +11 more
doaj   +2 more sources

Molecular epidemiology of Fonsecaea pedrosoi using mitochondrial DNA analysis [PDF]

open access: yesMedical Mycology, 1999
Restriction fragment length polymorphism (RFLP) of mitochondrial DNA (mtDNA) from 49 clinical Fonsecaea pedrosoi isolates (18 isolates from Japan, 17 from Madagascar, 7 from Argentina, 5 from Venezuela, 1 from Costa Rica and 1 unknown) was studied. The 49 isolates were composed of 20 isolates of Type 1, 16 of Type 2, 12 of Type 4 and 1 of a new mtDNA ...
M Miyaji, R Negroni, H Ishizaki
exaly   +3 more sources

Chromoblastomycosis due to Fonsecaea pedrosoi: an old wine in a rare bottle

open access: yesJournal of Infection in Developing Countries, 2015
Chromoblastomycosis is a chronic subcutaneous mycosis commonly caused by Fonsecaea, Phialophora, and Cladophialophora spp. Out of these, Fonsecaea pedrosoi is the most common etiological agent, implicated in 70%–90% of the cases reported worldwide.
Sadia Khan   +7 more
doaj   +4 more sources

Single-cell RNA sequencing unravels T cell exhaustion underlying the chronicity of chromoblastomycosis [PDF]

open access: yesFrontiers in Immunology
IntroductionChromoblastomycosis (CBM) is a chronic, neglected tropical fungal infection. Its immunopathogenesis, particularly the mechanism underlying its chronicity, remains poorly understood.MethodsWe performed single-cell RNA sequencing (scRNA-seq) on
Kexin Lei   +36 more
doaj   +2 more sources

Isolation of Fonsecaea pedrosoi from thorns of Mimosa pudica, a probable natural source of chromoblastomycosis

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 2004
We report the isolation of Fonsecaea pedrosoi from thorns of the plant Mimosa pudica L. at the place of infection identified by one of our patients. Clinical diagnosis of chromoblastomycosis was established by direct microscopic examination and cultures ...
Claudio Guedes Salgado   +6 more
doaj   +1 more source

Detection of delayed hypersensitivity to Fonsecaea pedrosoi metabolic antigen (chromomycin)

open access: yesNippon Ishinkin Gakkai Zasshi, 2008
An experimental study was conducted between January 2002 and April 2003 for the detection of delayed hypersensitivity to Fonsecaea pedrosoi metabolic antigen (chromomycin) in skin tests. A total of 194 subjects were attended by spontaneous demand at the Infectious and Parasitic Diseases outpatient clinic of the Federal University of Maranhão-UFMA and ...
Garcia Marques, Sirlei   +5 more
core   +5 more sources

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