Immunoprecipitation techniques and Elisa in the detection of anti-Fonsecaea pedrosoi antibodies in chromoblastomycosis [PDF]
Revista do Instituto de Medicina Tropical de São Paulo, 2003 Chromoblastomycosis (CBM) is a chronic subcutaneous infection caused by several dematiaceous fungi. The most commonly etiological agent found in Brazil is Fonsecaea pedrosoi, which appears as thick walled, brownish colored cells with transverse and ...
Vidal Mônica Scarpelli Martinelli +3 more
doaj +3 more sources
Comparison of Fonsecaea pedrosoi sclerotic cells obtained in vivo and in vitro: ultrastructure and antigenicity [PDF]
FEMS Immunology and Medical Microbiology, 2002 The parasitic form of Fonsecaea pedrosoi from the hyperkeratotic layer of the skin was obtained from four patients with chromoblastomycosis. Primary cultures containing hyphae and conidia were successfully converted into sclerotic cells in the presence ...
Alviano, Celuta Sales +6 more
core +4 more sources
A Case of Chromoblastomycosis Caused by Fonsecaea pedrosoi Successfully Treated by Oral Itraconazole Together with Terbinafine [PDF]
Dermatology and Therapy, 2020 Patients with chromoblastomycosis (CBM) usually have a history of local skin damage related to outdoor activities, mainly manifested as chronic refractory proliferative pathologic changes.
Xu-Cheng Shen +7 more
doaj +2 more sources
Bacillus subtilis induces morphological changes in Fonsecaea pedrosoi in vitro resulting in more resistant fungal forms in vivo [PDF]
Journal of Venomous Animals and Toxins including Tropical Diseases, 2010 Interactions among microorganisms may be the cause of morphological modifications, particularly in fungal cells. The aim of this work was to examine the changes that occur in cells of the fungus Fonsecaea pedrosoi after in vitro co-culturing with ...
AP Machado, M Anzai, O Fischman
doaj +4 more sources
Chromoblastomycosis Treatment With Combination Therapy of Itraconazole (Pulse Dose) and Cryotherapy [PDF]
Jurnal Profesi Medika, 2021 Chromoblastomycosis is a chronic mycosis infection of the skin and subcutaneous tissue. The lesson begins with a history of trauma characterized by slowly gradual growing nodule lesions, especially in the lower extremities.
Nugrohoaji Dharmawan, Ahmad Fiqri
doaj +3 more sources
Transformation of Fonsecaea pedrosoi into sclerotic cells links to the refractoriness of experimental chromoblastomycosis in BALB/c mice via a mechanism involving a chitin-induced impairment of IFN-γ production. [PDF]
PLoS Neglected Tropical Diseases, 2018 Fonsecaea pedrosoi (F. pedrosoi) is the most common agent of chromoblastomycosis. Transformation of this fungus from its saprophytic phase into pathogenic sclerotic cells in tissue is an essential link to the refractoriness of this infection ...
Bilin Dong +10 more
doaj +2 more sources
A chitin-like component on sclerotic cells of Fonsecaea pedrosoi inhibits Dectin-1-mediated murine Th17 development by masking β-glucans. [PDF]
PLoS ONE, 2014 Fonsecaea pedrosoi (F. pedrosoi), a major agent of chromoblastomycosis, has been shown to be recognized primarily by C-type lectin receptors (CLRs) in a murine model of chromoblastomycosis.
Bilin Dong +13 more
doaj +2 more sources
In Vitro Activities of Five Antifungal Drugs Against Conidia and Sclerotic Cells of Chromoblastomycosis Agent Fonsecaea spp. [PDF]
Microbiol ImmunolABSTRACT Chromoblastomycosis (CBM) is a chronic skin and subcutaneous infection mainly caused by Fonsecaea pedrosoi, a dematiaceous fungus with various morphotypes. Characteristic sclerotic cells—globe‐shaped, multiseptated and pigmented—are found in lesions of infected individuals, though their differentiation in the host remains poorly understood. To
Takahashi AB +6 more
europepmc +2 more sources
Characterization of Fonsecaea pedrosoi melanin [PDF]
Journal of General Microbiology, 1991 The constituents of the melanin complex from mycelial forms of Fonsecaea pedrosoi were partially characterized. The pigment was mainly accumulated on large alkali-extractable, electron-dense cytoplasmic bodies (melanosomes) and, apparently, on the outer layer of the cell wall as external deposits within verrucose outgrowths.
C S, Alviano +4 more
openaire +2 more sources
The impact of AlphaFold Protein Structure Database on the fields of life sciences
PROTEOMICS, Volume 23, Issue 17, September 2023., 2023 Abstract Arguably, 2020 was the year of high‐accuracy protein structure predictions, with AlphaFold 2.0 achieving previously unseen accuracy in the Critical Assessment of Protein Structure Prediction (CASP). In 2021, DeepMind and EMBL‐EBI developed the AlphaFold Protein Structure Database to make an unprecedented number of reliable protein structure ...
Mihaly Varadi, Sameer Velankar
wiley +1 more source