Melanin particles isolated from the fungus Fonsecaea pedrosoi activates the human complement system [PDF]
BACKGROUND Melanin production has been associated with virulence in various pathogenic fungi, including Fonsecaea pedrosoi, the major etiological agent for chromoblastomycosis, a subcutaneous fungal disease that occurs in South America.
Lysianne Pinto +7 more
doaj +3 more sources
The Major Chromoblastomycosis Etiologic Agent Fonsecaea pedrosoi Activates the NLRP3 Inflammasome [PDF]
Fonsecaea pedrosoi is the main etiologic agent of chromoblastomycosis (CBM), one of the most prevalent subcutaneous mycosis in tropical and subtropical countries.
Raffael Júnio Araújo de Castro +10 more
doaj +4 more sources
Immunoprecipitation techniques and Elisa in the detection of anti-Fonsecaea pedrosoi antibodies in chromoblastomycosis [PDF]
Chromoblastomycosis (CBM) is a chronic subcutaneous infection caused by several dematiaceous fungi. The most commonly etiological agent found in Brazil is Fonsecaea pedrosoi, which appears as thick walled, brownish colored cells with transverse and ...
Vidal Mônica Scarpelli Martinelli +3 more
doaj +6 more sources
Fonsecaea pedrosoi Sclerotic Cells: Secretion of Aspartic-Type Peptidase and Susceptibility to Peptidase Inhibitors [PDF]
Fonsecaea pedrosoi is a dematiaceous fungus and the main causative agent of chromoblastomycosis that is a chronic disease usually affecting the human skin and subcutaneous tissues, which causes deformations and incapacities, being frequently refractory ...
Vanila F. Palmeira +8 more
doaj +4 more sources
Fonsecaea Pedrosoi Skin Infection in a Dog [PDF]
Fonsecaea pedrosoi is the most common fungal agent associated with human chromoblastomycosis. In the current study, a phaeohyphomycotic condition of the skin caused by Fonsecaea pedrosoi is described in a dog.
Sreekumari, Rajeev +3 more
openaire +3 more sources
Characterization of Fonsecaea pedrosoi melanin [PDF]
The constituents of the melanin complex from mycelial forms of Fonsecaea pedrosoi were partially characterized. The pigment was mainly accumulated on large alkali-extractable, electron-dense cytoplasmic bodies (melanosomes) and, apparently, on the outer layer of the cell wall as external deposits within verrucose outgrowths.
C S, Alviano +4 more
openaire +3 more sources
Activation of the Alternative Complement Pathway by Fonsecaea pedrosoi [PDF]
Human sera were examined for evidence of complement activation by Fonsecaea pedrosoi. The serum that had been incubated with F. pedrosoi showed immunoelectrophoretic C3 conversion and generation of C5a, as measured by radioimmunoassay. C3 conversion and C5a generation did not occur in serum chelated with EDTA, or in serum heated to 56 degrees C for 30 ...
Torinuki, Wakio +3 more
openaire +3 more sources
Molecular Epidemiology of Fonsecaea Species [PDF]
To assess population diversities among 81 strains of fungi in the genus Fonsecaea that had been identified down to species level, we applied amplified fragment-length polymorphism (AFLP) technology and sequenced the internal transcribed spacer regions ...
Mohammad Javad Najafzadeh +7 more
doaj +3 more sources
Chromoblastomycosis Caused by Fonsecaea pedrosoi. [PDF]
We report herein a case of chromoblastomycosis caused by Fonsecaea (F.) pedrosoi in a 39-year-old male, who showed multiple, asymptomatic, scaly erythematous plaques on the left shin for 12 months. Histopathologically, chronic granulomatous inflammation and either sclerotic or muriform cells were observed.
Kim DM +6 more
europepmc +4 more sources
A Case of Chromoblastomycosis Caused by Fonsecaea pedrosoi Successfully Treated by Oral Itraconazole Together with Terbinafine [PDF]
Patients with chromoblastomycosis (CBM) usually have a history of local skin damage related to outdoor activities, mainly manifested as chronic refractory proliferative pathologic changes.
Xu-Cheng Shen +7 more
doaj +2 more sources

