HIV Aspartic Peptidase Inhibitors Modulate Surface Molecules and Enzyme Activities Involved with Physiopathological Events in Fonsecaea pedrosoi [PDF]
Frontiers in Microbiology, 2017 Fonsecaea pedrosoi is the main etiological agent of chromoblastomycosis, a recalcitrant disease that is extremely difficult to treat. Therefore, new chemotherapeutics to combat this fungal infection are urgently needed.
Vanila F. Palmeira +11 more
doaj +4 more sources
Fonsecaea pedrosoi Sclerotic Cells: Secretion of Aspartic-Type Peptidase and Susceptibility to Peptidase Inhibitors [PDF]
Frontiers in Microbiology, 2018 Fonsecaea pedrosoi is a dematiaceous fungus and the main causative agent of chromoblastomycosis that is a chronic disease usually affecting the human skin and subcutaneous tissues, which causes deformations and incapacities, being frequently refractory ...
Vanila F. Palmeira +8 more
doaj +4 more sources
Expanding the Toolbox for Functional Genomics in Fonsecaea pedrosoi: The Use of Split-Marker and Biolistic Transformation for Inactivation of Tryptophan Synthase (trpB) Gene [PDF]
Journal of Fungi, 2023 Chromoblastomycosis (CBM) is a disease caused by several dematiaceous fungi from different genera, and Fonsecaea is the most common which has been clinically isolated.
Luísa Dan Favilla +6 more
doaj +2 more sources
Study of tissue inflammatory response in different mice strains infected by dematiaceous fungi Fonsecaea pedrosoi [PDF]
Anais Brasileiros de Dermatologia, 2019 : Background: Diseases caused by melanized fungi include mycetoma, chromoblastomycosis and phaeohyphomycosis. This broad clinical spectrum depends on the dynamic interactions between etiologic agent and host.
Marilia Marufuji Ogawa +7 more
doaj +2 more sources
Melanin particles isolated from the fungus Fonsecaea pedrosoi activates the human complement system [PDF]
Memorias do Instituto Oswaldo Cruz, 2018 BACKGROUND Melanin production has been associated with virulence in various pathogenic fungi, including Fonsecaea pedrosoi, the major etiological agent for chromoblastomycosis, a subcutaneous fungal disease that occurs in South America.
Lysianne Pinto +7 more
doaj +2 more sources
Chromoblastomycosis Caused by Fonsecaea pedrosoi. [PDF]
Ann Dermatol, 2011 We report herein a case of chromoblastomycosis caused by Fonsecaea (F.) pedrosoi in a 39-year-old male, who showed multiple, asymptomatic, scaly erythematous plaques on the left shin for 12 months. Histopathologically, chronic granulomatous inflammation and either sclerotic or muriform cells were observed.
Kim DM +6 more
europepmc +4 more sources
Biofilm Formation by Chromoblastomycosis Fungi Fonsecaea pedrosoi and Phialophora verrucosa: Involvement with Antifungal Resistance [PDF]
Journal of Fungi, 2022 Patients with chromoblastomycosis (CBM) suffer chronic tissue lesions that are hard to treat. Considering that biofilm is the main growth lifestyle of several pathogens and it is involved with both virulence and resistance to antimicrobial drugs, we have
Ingrid S. Sousa +6 more
doaj +2 more sources
Tratamento de infecção corneana causado pelo Fonsecaea pedrosoi: relato de caso [PDF]
Arquivos Brasileiros de Oftalmologia, 2005 To report an unusual case of fungus keratitis due to Fonsecaea pedrosoi that developed after corneal trauma. Case report: A 18-year-old male presented with a corneal ulcer in the right eye, 28 days after a trauma with glass fragments.
Freitas, Denise de +7 more
core +7 more sources
Modulation of the immune response by Fonsecaea pedrosoi morphotypes in the course of experimental chromoblastomycosis and their role on inflammatory response chronicity. [PDF]
PLoS Negl Trop Dis, 2017 A common theme across multiple fungal pathogens is their ability to impair the establishment of a protective immune response. Although early inflammation is beneficial in containing the infection, an uncontrolled inflammatory response is detrimental and ...
Siqueira IM +10 more
europepmc +5 more sources
Fonsecaea pedrosoi-induced Th17-cell differentiation in mice is fostered by Dectin-2 and suppressed by Mincle recognition. [PDF]
Eur J Immunol, 2015 Funded by NIH.
Wüthrich M +6 more
europepmc +2 more sources