Results 31 to 40 of about 1,548 (182)

Transformation of Fonsecaea pedrosoi into sclerotic cells links to the refractoriness of experimental chromoblastomycosis in BALB/c mice via a mechanism involving a chitin-induced impairment of IFN-γ production. [PDF]

PLoS Neglected Tropical Diseases, 2018
Fonsecaea pedrosoi (F. pedrosoi) is the most common agent of chromoblastomycosis. Transformation of this fungus from its saprophytic phase into pathogenic sclerotic cells in tissue is an essential link to the refractoriness of this infection ...
Bilin Dong, Zhongsheng Tong, Ruoyu Li, Sharon C-A Chen, Weihuang Liu, Wei Liu, Yao Chen, Xu Zhang, Yiqun Duan, Dongsheng Li, Liuqing Chen   +10 more
doaj   +2 more sources

Fonsecaea pedrosoi as a rare cause of acute conjunctival ulceration

, 2016
ABSTRACT Conjunctival ulceration accompanied with secretion and pain was observed in a 30-year-old male, 3 days after a perforating corneal trauma. Cultures of conjunctival ulcer samples grew Fonsecaea pedrosoi, a major causative agent of chromoblastomycosis that is typically transmitted during trauma.
Adibelli, Fatih Mehmet, Karabicak, Nilgun, Akal, Ali, Goncu, Tugba, Yilmaz, Omer Faruk, Bayraktar, Mehmet   +5 more
openaire   +4 more sources

Fonsecaea pedrosoi cerebral phaeohyphomycosis ("chromoblastomycosis"): first human culture-proven case reported in Brazil

Revista do Instituto de Medicina Tropical de São Paulo, 2003
Cerebral phaeohyphomycosis ("chromoblastomycosis") is a rare intracranial lesion. We report the first human culture-proven case of brain abscesses due to Fonsecaea pedrosoi in Brazil.
José Paulo S. Nóbrega, Sergio Rosemberg, Ana Maria Adami, Elizabeth Maria Heins-Vaccari, Carlos da Silva Lacaz, Thales de Brito   +5 more
doaj   +1 more source

Cromoblastomicosis: abordaje con terapia combinada

Actualizaciones en Sida e Infectología, 2023
La cromoblastomicosis es una micosis de implantación crónica y progresiva, causada por diversos hongos de la familia Dematiaceae. En Latinoamérica, las especies encontradas con más frecuencia son Fonsecaea pedrosoi y Cladophialophora carrionii.
Viviana Leiro, Patricia Fernández Pardal, Mauro Coringrato, Ornela Piñeiro, Esteban Maronna, Gabriela Santiso   +5 more
doaj   +1 more source

In Vitro Activities of Five Antifungal Drugs Against Conidia and Sclerotic Cells of Chromoblastomycosis Agent Fonsecaea spp. [PDF]

Microbiol Immunol
ABSTRACT Chromoblastomycosis (CBM) is a chronic skin and subcutaneous infection mainly caused by Fonsecaea pedrosoi, a dematiaceous fungus with various morphotypes. Characteristic sclerotic cells—globe‐shaped, multiseptated and pigmented—are found in lesions of infected individuals, though their differentiation in the host remains poorly understood. To
Takahashi AB, Grisólia DPA, Silva MBD, Cruz NFD, Silva SMD, Costa PFD, Salgado CG.   +6 more
europepmc   +2 more sources

The impact of AlphaFold Protein Structure Database on the fields of life sciences

PROTEOMICS, Volume 23, Issue 17, September 2023., 2023
Abstract Arguably, 2020 was the year of high‐accuracy protein structure predictions, with AlphaFold 2.0 achieving previously unseen accuracy in the Critical Assessment of Protein Structure Prediction (CASP). In 2021, DeepMind and EMBL‐EBI developed the AlphaFold Protein Structure Database to make an unprecedented number of reliable protein structure ...
Mihaly Varadi, Sameer Velankar
wiley   +1 more source

First case of Rhinocladiella mackenziei brain abscess in Turkey: Case report and review of the literature

Mycoses, Volume 66, Issue 9, Page 755-766, September 2023., 2023
Abstract Rhinocladiella mackenziei is a highly neurotropic fungus, mainly reported from the Middle East. However, in recent years, there have been some cases from outside this region. We described an additional fatal case of R. mackenziei cerebral infection for the first time from Turkey and made a literature review of all previously reported cases ...
Ilvana Caklovica Kucukkaya, Cafer Ikbal Gulsever, Ilyas Dolas, Gonca Erkose Genc, Mert Ahmet Kuskucu, Pulat Akin Sabanci, Zayre Erturan   +6 more
wiley   +1 more source

C‐type lectin receptors in antifungal immunity: Current knowledge and future developments

Parasite Immunology, Volume 45, Issue 2, February 2023., 2023
Abstract C‐type lectin receptors (CLRs) constitute a category of innate immune receptors that play an essential role in the antifungal immune response. For over two decades, scientists have uncovered what are the fungal ligands recognized by CLRs and how these receptors initiate the immune response.
Remi Hatinguais, Janet A. Willment, Gordon D. Brown   +2 more
wiley   +1 more source

Molecular epidemiology and clinical‐laboratory aspects of chromoblastomycosis in Mato Grosso, Brazil

Mycoses, Volume 65, Issue 12, Page 1146-1158, December 2022., 2022
Abstract Introduction Chromoblastomycosis is a disease caused by melanized fungi, primarily belonging to the genera Fonsecaea and Cladophialophora, mainly affecting individuals who are occupationally exposed to soil and plant products. This research aimed to determine the clinical, epidemiological and laboratory characteristics of chromoblastomycosis ...
Armando Guevara, Andréia Ferreira Nery, Márcia de Souza Carvalho Melhem, Lucas Bonfietti, Anderson Messias Rodrigues, Ferry Hagen, Jamile Ambrósio de Carvalho, Zoilo Pires de Camargo, Bruna Jacomel F. de Souza Lima, Vânia Aparecida Vicente, Rosane Christine Hahn   +10 more
wiley   +1 more source

Assessing global fungal threats to humans

mLife, Volume 1, Issue 3, Page 223-240, September 2022., 2022
Abstract Fungi are an integral part of the earth's biosphere. They are broadly distributed in all continents and ecosystems and play a diversity of roles. Here, I review our current understanding of fungal threats to humans and describe the major factors that contribute to various threats.
Jianping Xu
wiley   +1 more source