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Research priorities in Fontan-associated liver disease
Current Opinion in Organ Transplantation, 2020Purpose of reviewFontan-associated liver disease (FALD) is an emerging condition in patients who have undergone surgical correction of univentricular congenital heart disease. There is little known about the epidemiology of FALD, including risk factors for end-organ failure or hepatocellular carcinoma nor a consensus on surveillance guidelines ...
Sara, Khan +2 more
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Fontan-Associated Liver Disease: Pathophysiology, Staging, and Management
Seminars in Liver Disease, 2021AbstractFontan-associated liver disease is the term used to encompass the disorders arising from abnormal hemodynamic alterations and systemic venous congestion after the Fontan procedure. The histological changes produced in the liver are similar but not equivalent to those seen in other forms of cardiac liver disease.
Luis Téllez +2 more
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Fontan‐associated liver disease after heart transplant
Pediatric Transplantation, 2022AbstractBackgroundFontan associated liver disease (FALD) potentially impacts Fontan patients undergoing heart transplant. This multi‐center study sought to identify pre‐transplant risk factors and characterize any post‐transplant liver recovery in those patients undergoing heart‐alone transplant.MethodsReview of Fontan patients at 12 pediatric ...
Eric R. Griffiths +17 more
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Surveillance of Fontan Associated Liver Disease in Childhood and Adolescence
Seminars in Thoracic and Cardiovascular Surgery, 2022Fontan associated liver disease (FALD) has been recognized as a potentially serious sequela of the Fontan circulation. Prevalence of FALD among different age groups and risk factors for advanced changes were assessed. FALD screening included abdominal ultrasound and laboratory tests. A "liver disease score (LDS)" incorporating items from ultrasound and
Jan Hinnerk Hansen +7 more
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Severity of Fontan-Associated Liver Disease Correlates with Fontan Hemodynamics [PDF]
AbstractFontan-palliated patients are at risk for the development of Fontan-associated liver disease (FALD). In this study, we performed a detailed hemodynamic and hepatic assessment to analyze the incidence and spectrum of FALD and its association with patients' hemodynamics.
Anastasia Schleiger +2 more
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Fontan-Associated Liver Disease: A Review
Cardiology in ReviewFontan-associated liver disease (FALD) is a chronic complication of the Fontan procedure, a palliative surgery for patients with congenital heart disease that results in a single-ventricle circulation. The success of the Fontan procedure has led to a growing population of post-Fontan patients living well into adulthood.
Gabriel, Heering +4 more
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Portal vein thrombosis in Fontan-associated liver disease
Cardiology in the Young, 2020AbstractA 25-year-old patient with signs of cirrhosis on ultrasound and CT presented with portal vein thrombosis on routine follow-up examinations; retrograde hepatic wedge angiography demonstrated only the right-sided portal vein branch. Development of a portosystemic collateral vessel to the left-sided renal vein prevented signs of hypersplenism ...
Renate Kaulitz +2 more
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Fontan-associated liver disease: Spectrum of US findings
European Journal of Radiology, 2016To describe ultrasonography (US) findings of Fontan-associated liver disease (FALD) and to determine whether screening US examinations can identify FALD before biochemical hepatic dysfunction.This retrospective study included 55 patients who underwent Fontan procedure over a 20-year period.
Jung Min, Bae +6 more
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Fontan associated liver disease: Is elastography useful?
Progress in Pediatric Cardiology, 2020Abstract Introduction Fontan associated liver disease (FALD), can manifest in the form of abnormal liver function tests to cirrhosis to hepato cellular carcinoma. Onset of liver disease in such patients can go unnoticed for years if only synthetic function of liver is looked at or till the clinical symptoms appear.
Adhi Arya, Sushil Azad, S. Radhakrishnan
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