Results 121 to 130 of about 1,450,853 (311)

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

Leadership, Violence, and Warfare in Small Societies [PDF]

open access: yes
Multi-agent simulation was used to study the effect of simple models of leadership on interpersonal violence and warfare in small societies. Agents occupied a two dimensional landscape containing villages and food sources.
Stephen Younger
core  

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Science and poverty [PDF]

open access: yes
"Agricultural research has greatly increased the yields of important staple food crops, and for many people this has meant more food availability and trade opportunities. Yet many people in rural areas in developing countries still live in abject poverty.
Adato, Michelle   +3 more
core  

Do we all perceive food-related wellbeing in the same way? : results from a cross-cultural [PDF]

open access: yes, 2015
Interest in measuring consumers' perceived wellbeing in a food-related context has been growing. Understanding how foods influence consumers' perceived wellbeing can contribute to better understand eating patterns.
Ares, Gastón   +9 more
core  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

Changing pattern of malaria in Bissau, Guinea Bissau.

open access: yes, 2008
OBJECTIVE: To describe the epidemiology of malaria in Guinea-Bissau, in view of the fact that more funds are available now for malaria control in the country.
Aaby, Peter   +4 more
core   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

Vocabulary data presented in the local traditions of central Java and East JavaMendeley Data

open access: yesData in Brief
This article explores the extensive vocabulary linked to traditional cuisine among the Javanese people in Indonesia, specifically focusing on five regions in East Java and eight regions in Central Java.
Nirbito Hanggoro Pribadi   +5 more
doaj   +1 more source

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