Results 101 to 110 of about 735,917 (290)

USE OF ANTI-INFECTIVE MEDICATIONS VIA THE GASTROSTOMY CATHETER: RECOMMENDATIONS FOR NURSING

open access: yesCogitare Enfermagem, 2018
Objective: to present specific recommendations in the preparation and administration of anti-infective medications via the gastrostomy catheter in the Emergency Unit of a University Hospital in the South of Brazil.
Moara Avila de Jesus Moreira   +5 more
doaj   +1 more source

Fluoxetine: a case history of its discovery and preclinical development [PDF]

open access: yes, 2014
Introduction: Depression is a multifactorial mood disorder with a high prevalence worldwide. Until now, treatments for depression have focused on the inhibition of monoaminergic reuptake sites, which augment the bioavailability of monoamines in the CNS ...
Bel N   +20 more
core   +2 more sources

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

open access: yesFEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

open access: yesFEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli   +9 more
wiley   +1 more source

Food interactions with tyrosine kinase inhibitors used to treat advanced renal cell carcinoma

open access: yesContemporary Oncology
Renal cancer accounts for approximately 4.4% of all malignant tumors worldwide. In the case of tumors limited to the kidney, the primary method of treatment is surgery.
Agata Sałek-Zań   +3 more
doaj   +1 more source

Development of Chitosan/Gelatin/Keratin Composite Containing Hydrocortisone Sodium Succinate as a Buccal Mucoadhesive Patch to Treat Desquamative Gingivitis [PDF]

open access: yes, 2018
The aim of this research was to develop chitosan/gelatin/keratin composite containing hydrocortisone sodium succinate as a buccal mucoadhesive patch to treat desquamative gingivitis, which was fabricated through an environmental friendly process ...
Davoudi, Zahra   +7 more
core   +1 more source

The Computational Diet: A Review of Computational Methods Across Diet, Microbiome, and Health. [PDF]

open access: yes, 2020
Food and human health are inextricably linked. As such, revolutionary impacts on health have been derived from advances in the production and distribution of food relating to food safety and fortification with micronutrients. During the past two decades,
Eetemadi, Ameen   +5 more
core  

TMC4 localizes to multiple taste cell types in the mouse taste papillae

open access: yesFEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata   +6 more
wiley   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

EVALUATION OF PHARMACY EMPLOYEES’ USAGE OF HERBAL PRODUCTS AND KNOWLEDGE ABOUT FOOD–DRUG INTERACTIONS

open access: yesSabiad
Objective: This study was conducted to determine and compare herbal product use, attitudes toward herbal products, and the knowledge about food–drug interactions of pharmacy employees.
Yasemin Ertaş Öztürk   +3 more
doaj   +1 more source

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