Results 41 to 50 of about 957,143 (265)

Query selection methods for automated corpora construction with a use case in food-drug interactions

open access: yesBioNLP@ACL, 2019
In this paper, we address the problem of automatically constructing a relevant corpus of scientific articles about food-drug interactions. There is a growing number of scientific publications that describe food-drug interactions but currently building a ...
Georgeta Bordea   +4 more
semanticscholar   +1 more source

Influence of Food on Paediatric Gastrointestinal Drug Absorption Following Oral Administration: A Review

open access: yesChildren, 2015
The objective of this paper was to review existing information regarding food effects on drug absorption within paediatric populations. Mechanisms that underpin food–drug interactions were examined to consider potential differences between adult and ...
Hannah K. Batchelor
doaj   +1 more source

Role of food‑drug interactions in neurological and psychological diseases.

open access: yesActa Neurobiologiae Experimentalis, 2018
Given that foods and nutrients have been shown to influence the pharmacokinetics of drugs, drugs may cause changes in the nutritional status of patients and their response to a given drug.
M. Gezmen-Karadağ   +5 more
semanticscholar   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Nurses' Awareness and Perception of Drug-Drug and Drug Food Interactions

open access: yesEvidence-Based Nursing Research
Context: The issue of drug interactions is a global concern. Studies reported a high prevalence of drug interactions worldwide. The drug-drug interaction (DDIs) and drug-food interactions (DFIs) are often predictable and preventable.
Hend A. E. Elshenawi   +1 more
doaj   +1 more source

POMELO: Medline corpus with manually annotated food-drug interactions

open access: yesBiomedicalNLP@RANLP, 2017
When patients take more than one medication, they may be at risk of drug interactions, which means that a given drug can cause unexpected effects when taken in combination with other drugs.
Thierry Hamon   +4 more
semanticscholar   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Identification of Probable Drug-Drug and Drug-Food Interactions in Hospitalized Patients With Chronic Renal Disease

open access: yesPharmacology and Clinical Pharmacy Research
Chronic renal disease is a substantial health challenge in numerous countries worldwide, including Indonesia. Chronic renal disease patients frequently experience comorbidities and require multiple medications (polypharmacy).
Okta M. Sari, Aditya M.P Putra
doaj   +1 more source

Pharmacokinetic Drug-Drug Interactions with Drugs Approved by the US Food and Drug Administration in 2020: Mechanistic Understanding and Clinical Recommendations

open access: yesDrug Metabolism And Disposition, 2021
Drug-drug interaction (DDI) data for small molecular drugs approved by the US Food and Drug Administration in 2020 (N = 40) were analyzed using the University of Washington Drug Interaction Database.
Jingjing Yu   +2 more
semanticscholar   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

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