Results 41 to 50 of about 449,984 (280)
Children, 2015 The objective of this paper was to review existing information regarding food effects on drug absorption within paediatric populations. Mechanisms that underpin food–drug interactions were examined to consider potential differences between adult and ...
Hannah K. Batchelor
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Nurses' Awareness and Perception of Drug-Drug and Drug Food Interactions
Evidence-Based Nursing ResearchContext: The issue of drug interactions is a global concern. Studies reported a high prevalence of drug interactions worldwide. The drug-drug interaction (DDIs) and drug-food interactions (DFIs) are often predictable and preventable.
Hend A. E. Elshenawi +1 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Pharmacology and Clinical Pharmacy ResearchChronic renal disease is a substantial health challenge in numerous countries worldwide, including Indonesia. Chronic renal disease patients frequently experience comorbidities and require multiple medications (polypharmacy).
Okta M. Sari, Aditya M.P Putra
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Dangerous food-drug interactions
, 2014 Aim: To increase patients` awareness of the health risks of certain drug-food interactions and to present their competence in the problem.Materials and methods: Systematic approach of available scientific literature on the problem and specially designed ...
Stoeva, Stanila; Medical University of Varna +2 more
core +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Role of food-drug interactions in neurological and psychological diseases [PDF]
, 2018 Given that foods and nutrients have been shown to influence the pharmacokinetics of drugs, drugs may cause changes in the nutritional status of patients and their response to a given drug.
Kadayifçi, Fatma Zehra +11 more
core +2 more sources
Pharmacy, 2021 Introduction: Various drug–food interactions exist that may hinder treatment and can sometimes be lethal. Our aim was to assess the level of public knowledge and awareness in Jeddah city, Western Saudi Arabia, about drug–food interactions, along with the
Syed Faisal Zaidi +6 more
doaj +1 more source