Results 101 to 110 of about 4,652,448 (317)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Food Digest : 2014 [PDF]

open access: yes, 2014
Message from the Department Head: Greetings. December 10, 2013, is a date that should be recorded as part of the Food Science and Technology history. On this date we received a Temporary Certificate of Occupancy for the Human and Agricultural Biosciences
Virginia Tech. Food Science and Technology Department
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

How Sicily Made Its Sweet Symbols: Glocal Identity and Food

open access: yesGlocalism: Journal of Culture, Politics and Innovation, 2020
Food is an effective symbol capable of strongly evoking a cultural identity. In the case of Sicily, this role is mainly played by pastry, and in particular by two sweets: cannolo (the singular of cannoli) and cassata.
Dario Mangano
doaj  

La redéfinition des plats et des pratiques alimentaires populaires au Mexique 

open access: yesIdeAs, 2013
Based on research concerning tacos, this article shows, how lower class meals and practices spread to all social milieu. Neither social differences nor symbolic relations among classes disappear through this type of consumption, which actually highlights
Domingo Garcia-Garza
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Association of dietary intake with a risk factor of atherosclerosis – abdominal obesity in men of Novosibirsk

open access: yesАтеросклероз, 2015
Aim. To evaluate association between the nutrition habits and abdominal obesity in cross-sectional population study among men 45-69 years in Novosibirsk. Materials and methods.
A. K. Kuntsevich   +5 more
doaj  

Food production and food safety

open access: yesBMJ, 1999
Editorials by Brundtland and Pershagen Most food is now produced by large farms, processed industrially, and sold in supermarkets and multinational food outlets. Modern food production has reduced the cost and increased the variety of food available, but this centralisation of the food supply presents an opportunity for foodborne pathogens and toxins
openaire   +3 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

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