Results 81 to 90 of about 4,638,101 (317)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
, 2015 Message from the Department Head: Greetings! I hope this newsletter gives you an indication of the Department of Food Science and Technology’s busy year.
Virginia Tech. Food Science and Technology Department
core
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
The bromides of gods, the passions of humans
NWIG, 1996 [First paragraph] Histoire du chocolat. NlKlTA HARWICH. Paris: Desjonquères, 1992. 292 pp. (Paper, n.p.) The Chocolate Tree: A Natural History of Cacao. ALLEN M. YOUNG. Washington DC: Smithsonian Institution Press, 1994. xv + 200 pp. (Cloth US$
Sidney W. Mintz
doaj
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
, 2013 IFPRI in collaboration with UNICEF and WFP conducted a study of the effectiveness of food and cash transfers linked to participation in an Early Childhood Development (ECD) program in Uganda.
World Food Program (WFP) +2 more
core +1 more source
The Use of Medical Foods to Fight Chronic Diseases: A Narrative Review
Journal of Agricultural SciencesChronic diseases cannot be treated completely, and, therefore, often require repeated treatments. This issue leads to long-term drug utilization. However, medical foods can offer alternative natural drugs in the management and treatment of chronic ...
Aslihan Demirdöven, Hilal Meral
doaj +1 more source