Results 71 to 80 of about 4,638,101 (317)
Food craving in food addiction
Food craving refers to an intense desire to consume a specific type of food. This chapter describes features of food craving (such as the type of foods craved, sex and cultural differences, its distinctiveness from hunger, and psychological theories on the emergence of food cravings) and their role in addiction-like eating behavior.
openaire +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
copyright UK Data Service and data collection copyright owner.The Food and You Surveys (2010-2018), and Food and You 2 (2020- ) are bi-annual, cross-sectional surveys of adults aged 16 years and over living in England, Wales and Northern Ireland,  ...
Food Standards Agency, TNS-BMRB
core +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Design and Validation of Web- Based Persian Food Composition to Eevaluate Energy and Nutrients Intake: A Basic Applied Study Using the Data From the Ravanser Cohort Study [PDF]
Background and Aim: For accurate dietary intake assessments, the need for accurate and valid tools is urgent. These tools, in addition to easy use, immediately show a complete analysis of food intake in the form of macronutrients and micronutrients.
Yahya Pasdar +4 more
doaj
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Food and You 2: Waves 1-9, 2020-2024
copyright UK Data Service and data collection copyright owner.The Food and You Surveys (2010-2018), and Food and You 2 (2020- ) are bi-annual, cross-sectional surveys of adults aged 16 years and over living in England, Wales and Northern Ireland,  ...
Food Standards Agency
core
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source

