Results 71 to 80 of about 2,808,465 (219)

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Food and health-contribute of agri-food economics

Italian Journal of Agronomy, 2009
The analysis of the relationship between food and health in a context of innovation, safety and welfare is carried out considering the view of agri-food economists. Relationships and meanings are addressed defining by the scope of observation and choices.
Franco Baraldi, Maurizio Canavari, Domenico Regazzi, Roberta Spadoni   +3 more
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Culture-Based Standard Methods for the Isolation of Campylobacter spp. in Food and Water

Polish Journal of Microbiology
Campylobacter spp. is a major source of global gastrointestinal infections. Their enteric infections are linked to the consumption of undercooked poultry products, contaminated milk and water, and the handling of wild animals and birds.
Neyaz Leena A., Arafa Sara H., Alsulami Fatimah S., Ashi Hayat, Elbanna Khaled, Abulreesh Hussein H.   +5 more
doaj   +1 more source

Essential Oil from the Leaves of the Dwarf Cashew Tree (Anacardium occidentale L.) in the Amazon Savannah: Physicochemical and Antioxidant Properties as a Food Preservative

Foods
Anacardium occidentale, known as cashew tree, is widely used in the Amazon. This study aimed to evaluate the chemical composition, as well as the biological, physicochemical, antioxidant, and acceptability properties, of the essential oil (EO) extracted ...
Maria Clarisnete de Oliveira Moura, Esther Morais da Silva Assuncão, Salatiel Silva Barbosa, Edu Istarley Lourenço Tenente, Alessandro Pereira de Souza, Rajá Vidya Moreira dos Santos, Ana Paula Folmer Correa, Laura Adriane de Moraes Pinto, Amélia Carlos Tuler, Daniela Cavalcante dos Santos Campos, Marcos Jose Salgado Vital, Antonio Alves de Melo Filho, Jéssica de Oliveira Monteschio   +12 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

The availability, price, and marketing characteristics of organic foods and beverages: a comparative food environment assessment

Frontiers in Sustainable Food Systems
BackgroundDemand for organic foods remains low, despite the potential of organic products to contribute to sustainable food systems. Food purchasing decisions are influenced by the food environment, yet no study has systematically evaluated food ...
Alexandra Sadler, Yandrapu Bharath, Jacqueline Tereza da Silva, Daniel Carneiro de Abreu, Emily Shankar, Karolyne Vieira Bassetto, Lindsay Jaacks   +6 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Potency of coffee by-products as sustainable added material in bio/edible film development

Frontiers in Sustainable Food Systems
Coffee processing generates abundant by-products including husk, pulp, spent coffee grounds, and silver skin, which pose environmental challenges but potential as functional materials.
Ata Aditya Wardana, Noor Ariefandie Febrianto, Vincensius Marcellino, Laras Putri Wigati, Francis Ngwane Nkede, Fumina Tanaka, Fumihiko Tanaka   +6 more
doaj   +1 more source