Results 61 to 70 of about 8,967,367 (265)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Ración alimentaria: asuntos de biopolítica en la escuela colombiana de principios del siglo XX [PDF]

open access: yesCabás, 2012
Nos adentramos en las relaciones entre la escuela, la infancia y la sociedad, mediadas por prácticas alimentarias que se producen en forma de políticas educativas y sociales, cuyo propósito se inscribe en el gobierno de la población, en la pretensión ...
Beltrán, C. X. H., Ángel, J. B. G.
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Algunos culturemas de alimentación en Pedro Páramo y su traducción al árabe [PDF]

open access: yesEstudios Interlingüísticos, 2019
Este artículo analiza los culturemas referentes a la alimentación en la novela Pedro Páramo de Juan Rulfo y su traducción al árabe, mediante el análisis de las técnicas de traducción usadas por tres traductores árabes.
Najlaa Kounitrate
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

PortFIR – An integrated data provider as support for the food policy-makers [PDF]

open access: yes, 2019
Introduction: Portuguese Food Composition Table (TCA) is managed by the National Institute of Health Doutor Ricardo Jorge (INSA) and is publicly available on the Portuguese Food Information Resource (PortFIR) platform.
Brazão, Roberto   +4 more
core  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Unlocking the Potential of Mannosylerythritol Lipids: Properties and Industrial Applications

open access: yesFermentation
Mannosylerythritol lipids (MELs), one of the most promising biosurfactants (BS), are glycolipids produced by yeasts or fungi, which have great environmental performance and high compatibility with the human body.
Joana Dias de Almeida   +4 more
doaj   +1 more source

Shopping for Food [PDF]

open access: yes, 2017
Postcard from Andrew Hampson, during the Linfield College Semester Abroad Program at Aoyama Gakuin University in Sagamihara ...
Hampson, Andrew
core   +1 more source

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