Results 191 to 200 of about 9,350,244 (365)

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Safety evaluation of the food enzyme arabinan endo-1,5-α-L-arabinanase from the non-genetically modified <i>Aspergillus aculeatinus</i> strain CBS 148915. [PDF]

open access: yesEFSA J
EFSA Panel on Food Enzymes (FEZ)   +17 more
europepmc   +1 more source

The Islamic Foundations of Halal Food Gastronomy in ‎Malaysia ‎

open access: yesRabbanica: Journal of Revealed Knowledge
The current scenario is witnessing halal food culture being widely practised by Muslims and non-Muslim because of their confidence in its quality in terms of safety, hygiene, and nutrient composition.
Siti Jamilah Mohd Sukri   +3 more
doaj  

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

open access: yesFEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani   +7 more
wiley   +1 more source

Research progress on the metabolic transformation of Shenling Baizhu San under the influence of the gut microbiota

open access: yesAdvanced Chinese Medicine, EarlyView.
Abstract The gut microbiota plays a pivotal role in maintaining host metabolic homeostasis and overall physiological functions. Shenling Baizhu San (SLBZS), a time‐honored classical prescription for tonifying Qi, strengthening the spleen, removing dampness, and arresting diarrhea, has shown broad clinical efficacy in digestive disorders.
Jinlan Di, Xiaochun Zhang
wiley   +1 more source

Safety evaluation of the food enzyme glucan 1,4-α-maltohydrolase from the genetically modified <i>Trichoderma reesei</i> strain DP-Nyn90. [PDF]

open access: yesEFSA J
EFSA Panel on Food Enzymes (FEZ)   +16 more
europepmc   +1 more source

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