Results 91 to 100 of about 3,014,246 (287)

Etiology of Food Addiction

Psikiyatride Güncel Yaklaşımlar, 2012
Food addiction is a new topic of focus in the scientific literature. Food intake might be concerned as food addiction in some cases, especially in obese cases and over-eaters. Addiction like behaviours are commonly observed mong these people.
Demet Gulec Oyekcin, Artuner Deveci
doaj  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Internet sex addiction: a review of empirical research [PDF]

, 2012
The advent of the internet has added another medium in which people can engage in sexual behaviour. This ranges from the passive consumption of online pornography to the interactive exchange of sexual content in cybersex chat rooms.
Griffiths, MD
core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Exercise addiction – the emergence of a new disorder [PDF]

, 2014
An optimal level of regular physical activity plays an important role in the maintenance of physical and mental health. However, excessive exercise in a minority of individuals can have adverse effects on health and lead to exercise addiction.
Demetrovics, Zsolt, Szabó, Attila, Berczik, K, Griffiths, MD, Kökönyei, Gyöngyi, Szabó, A, Kurimay, T, Urbán, R, Kökönyei, G, Urbán, Róbert, Demetrovics, Z, Kurimay, Tamás, Berczik, Krisztina, Griffiths, Mark   +13 more
core  

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

COMPARISON OF PHYSICAL ACTIVITY LEVEL AND FOOD ADDICTION OF PHYSICAL EDUCATION AND SPORTS SCIENCE COLLEGE STUDENTS [PDF]

Sportif Bakış Spor ve Eğitim Bilimleri Dergisi, 2017
The aim of this study is to examine the physical activity level and food addiction of physical education and sport science students and to investigate the excessive food consumption. In the study in order to evaluate food addiction of students “Yale Food
Mert Kayhan, Alparslan Ünveren
doaj  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Addiction, Social Interactions and Gender Differences in Cigarette Consumption [PDF]

This paper addresses the impact of addiction and social interactions on cigarette demand, controlling for demographic and socioeconomic factors. A Box-Cox double-hurdle model for the simultaneous decisions of how much to smoke and whether to quit smoking
David Aristei, Luca Pieroni
core  

Severe depression association with the addiction to fast food and smartphones in Jordanians: a cross-sectional study

Discover Food
Background The connection between psychiatry health, mental health, and lifestyle is under-studied in the Arab world. This study examined whether addictions to smartphones and fast food are associated with severe depressive symptoms in a cohort of Arab ...
Nawal AlSakarneh, Dana Kakeesh, Khaled Al-Marazeeq, Ali Ahmad Banysaed, Omar Gammoh   +4 more
doaj   +1 more source