Results 61 to 70 of about 2,854,780 (304)

Leptin May Promote Eosinophilic CRSwNP Progression by Enhancing Eosinophil Chemotaxis and Angiogenesis Under a Type 2 Inflammatory Milieu

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyp (CRSwNP) is a heterogeneous Type 2 inflammatory disease characterized by enhanced eosinophilic infiltration. Both innate and adaptive immunity are involved in the onset and progression of CRSwNP.
Yuki Sonoda   +4 more
wiley   +1 more source

Stability of the Bet v 1 cross-reactive allergens Api g 1 and Dau c 1 : a biophysical approach [PDF]

open access: yes, 2009
The allergen Bet v 1 is known as the primary sensitizer for birch pollen-related food allergy and is responsible for IgE cross-reactivity to pathogenesis-related 10 (PR-10) proteins from, in particular, fruits from the Rosaceae and vegetables from the ...
Bollen, M.A.
core  

Development of a Sandwich ELISA to Measure Exposure to Occupational Cow Hair Allergens [PDF]

open access: yes, 2011
Background: Cow hair and dander are important inducers of occupational allergies in cattle-exposed farmers. To estimate allergen exposure in farming environments, a sensitive enzyme immunoassay was developed to measure cow hair allergens.
Spickenheuer, Anne   +23 more
core   +1 more source

Performance Assessment and Lab‐Scale Economic Evaluation of Alkaline Extraction and Comparative Precipitation of Cyanobacterial Proteins

open access: yesAsia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Algal proteins from cyanobacteria serve as a natural source of biopolymers. The principal challenge manifests as nonoptimization of unit operations in downstream process accounting for higher costs. This study focuses on process assessment of unit‐operations for selecting suitable recovery strategies not only based on yield, but also considers
Neha Goel   +2 more
wiley   +1 more source

Dissecting the dissection laboratory: Elements for designing a human anatomy laboratory

open access: yesAnatomical Sciences Education, EarlyView.
Abstract The human anatomy dissection laboratory is a critical component of anatomical and medical education. Development, maintenance, and stocking of these laboratory spaces have unique demands, with all of the challenges in running a laboratory with Biosafety Laboratory Level 2 (BSL‐2) classification, housing a large volume of tissues saturated with
Rhiannon E. Robinson   +13 more
wiley   +1 more source

Pharmacokinetics and safety of tezepelumab in children with mild, moderate or severe asthma and adolescents with mild‐to‐moderate asthma

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Tezepelumab is a human monoclonal antibody that blocks the activity of thymic stromal lymphopoietin and is approved for adolescents and adults with severe asthma. This analysis assessed pharmacokinetics (PK), pharmacodynamics and safety of tezepelumab up to 85 days postdose in adolescents and children.
Anna Lundahl   +14 more
wiley   +1 more source

Maternal Factors That Influence the Presence of Food Allergens in Human Milk—A Systematic Review

open access: yesProceedings
Food allergens have been detected in human milk with wide frequency and concentration variations between women. As maternal factors such as age, body mass index (BMI), and allergic disease influence human milk composition, we aimed to identify which ...
Sophie A. Hughes   +4 more
doaj   +1 more source

Histamine and the mechanisms of nausea and vomiting: Translating the uncertain pharmacology of cyclizine

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Cyclizine is a long‐established, short‐acting drug, registered for preventing motion sickness, post‐operative nausea and vomiting (PONV) and ‘vomiting of known cause’. The latter is not defined but may include pregnancy and patients receiving palliative care, historically accepted without large, controlled trials.
Gareth J. Sanger, Paul L. R. Andrews
wiley   +1 more source

The Impact of Glycation on Protein Digestibility

open access: yesChemFoodChem, EarlyView.
Schematic overview of how protein glycation affects digestibility and downstream nutritional consequences. Glycation‐derived structural modifications reduce protease accessibility, leading to limited hydrolysis and altered peptide generation. These changes decrease amino acid bioavailability and may subsequently contribute to microbiome alterations ...
Lea Hönemann   +2 more
wiley   +1 more source

Current Trends in Proteomic Advances for Food Allergen Analysis

open access: yesBiology, 2020
Food allergies are a global food challenge. For correct food labelling, the detection and quantification of allergens are necessary. However, novel product formulations and industrial processes produce new scenarios, which require much more technological
María López-Pedrouso   +3 more
doaj   +1 more source

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