Results 61 to 70 of about 5,531,710 (302)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Journal of Food ProtectionListeria monocytogenes is a foodborne pathogen that can survive at refrigerated temperatures. However, data on L. monocytogenes contamination in food court settings are lacking. We investigated the prevalence and characteristics of L.
Jeong-Eun Lee +3 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Food Access and Food Security – An Empirical Analysis [PDF]
This paper analyzes the effect of access to different types of food outlets on households’ food insecurity levels. Two years (2004 and 2005) of Current Population Survey – Food Security Supplement data are matched with MSA-level data on store counts of ...
Bonanno, Alessandro, Li, Jing
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Analysis of carbonylated proteins in cake formulations added with whey protein
Revista Brasileira de Nutrição Esportiva, 2023 Chemical modifications in cake formulations made with whey protein and subjected to high temperatures undergo the formation of carbonylated proteins which is a biomarker of protein oxidation.
Alisson de Carvalho Gonçalves +5 more
doaj
ANALYSIS OF FOOD STAMP PROGRAM PARTICIPATION AND FOOD EXPENDITURES [PDF]
A two equation model is developed to examine jointly the determinants of household food stamp program participation and program effects on food expenditures.
Blaylock, James R., Smallwood, David M.
core +1 more source
No. 09: Comparing Household Food Security in Cities of the Global South through a Gender Lens [PDF]
, 2017 Understanding the determinants of urban food insecurity requires sensitivity to local cultural contexts and taking into account a globally relevant framework for analysis.
Caesar, Mary, Riley, Liam
core +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source