Results 71 to 80 of about 5,531,710 (302)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Strecker degradation products of aspartic and glutamic acids and their amides

open access: yesCzech Journal of Food Sciences, 2001
Aspartic and glutamic acids, asparagine and glutamine were oxidised with either potassium peroxodisulphate or glyoxal. Nonvolatile products were derivatised and analysed by GC/FID and GC/MS.
J. Rössner   +3 more
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Comprehensive Evaluation of OS Starch–Oleic Acid Mixtures: From Functional Properties to Their Application in Films with Improved Water Resistance

open access: yesMolecules
This study investigated the effects of octenyl succinate (OS) starches mixed with oleic acid on functional properties and potential use in edible films. Potato starches esterified with 1%, 3%, 5%, or 7% of octenyl succinic anhydride (OSA) were mixed with
Karolina Królikowska   +4 more
doaj   +1 more source

Determination of astringent taste in model solutions and in beverages

open access: yesCzech Journal of Food Sciences, 2001
The astringent taste is important for the sensory quality of beverages. Perception thresholds of two important astringent compounds - tannic acid and (+)-catechin were determined using two procedures.
H. Valentová   +3 more
doaj   +1 more source

Evaluating sustainability in the UK fast food supply chain: Dimensions, Awareness and Practice [PDF]

open access: yes, 2014
Purpose - This paper investigates the level of concern and practice of sustainable management in the fast food supply chain in the North of England, targeting a business population with cultural, social and economic diversity.
Nabhani, Farhad   +2 more
core   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Consumer Power to Change the Food System? A Critical Reading of Food Labels as Governance Spaces: The Case of Acai Berry Superfoods [PDF]

open access: yes, 2019
This article argues that the marketing claims on food labels are a governance space worthy of critical examination. We use a case study of superfood açaí berry products to illustrate how marketing claims on food labels encapsulate dominant neoliberal ...
Curll, Janine   +2 more
core   +2 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Ability of phenolic acids to protect naturally present alfa-tocopherol during the heating of plant oils

open access: yesCzech Journal of Food Sciences, 2012
The ability of phenolic acids (ferulic, gallic, protocatechuic, and sinapic; 600 mg/kg) to protect naturally present a-tocopherol was tested during the heating of sunflower oil on a hot plate set at 120, 150, 180, 210, or 240°C, and during the heating of
Zuzana RÉBLOVÁ   +4 more
doaj   +1 more source

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