Results 91 to 100 of about 1,015,538 (309)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The first host plant dataset of Curculionidae Scolytinae of the world: miscellaneous Tribes

Scientific Data
Tribes Coriacephilini, Corthylini, Cryphalini, Ernoporini, Trypophloeini, Xyloctonini, and Xyloterini (Coleoptera: Curculionidae; Scolytinae) include spermophagous, phloeophagous, and xylomycetophagous species.
Matteo Marchioro, Davide Vallotto, Enrico Ruzzier, Laura Besana, Michele Rossini, Giacomo Ortis, Massimo Faccoli, Isabel Martinez-Sañudo   +7 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Animals and ambivalence, governing farm animal welfare in the European food sector [PDF]

That humans exploit animals, often in cruel ways, is not open to doubt. Reponsibility for exploitation and cruelty lies unambiguously on the human side of any human-animal divide.
Miele, Mara, Roe, Emma, Murdoch, Jonathan   +2 more
core  

Safety of pyrroloquinoline quinone disodium salt as a novel food pursuant to Regulation (EC)No 258/97 [PDF]

, 2017
Following a request from the European Commission, the EFSA Panelon Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on pyrroloquinoline quinone disodium salt (PQQ), trade name BioPQQ, as a novel food pursuant to Regulation
Heinonen, Marina, EFSA Panel Dietetic Prod Nutr   +1 more
core   +1 more source

Gut morphology and blood biochemical parameters of growing pigs fed diets with a partial to total replacement of soybean meal with Arthrospira platensis

Frontiers in Veterinary Science
Soybean meal is the primary protein source in pig diets, but its production has been associated with deforestation, soil degradation, and loss of biodiversity. Arthrospira platensis (AP), a protein-rich cyanobacterium with a favorable amino acid profile,
Diana Giannuzzi, Alessandro Toscano, Gregorio Don, Rina Verdiglione, Stefano Schiavon, Luigi Gallo   +5 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Antimicrobial resistance monitoring results complementing the EU Overview Summary Report on AMR in zoonotic and indicator bacteria from humans, animals and food in 2017/2018 - Estonia [PDF]

, 2020
This dataset contains AMR monitoring results in animals and food at the isolate level pursuant to Article 9 of Directive 2003/99/EC and to Annex, part B, of Commission implementing Decision 2013/652/EU. In addition, the dataset includes any other results
Veterinary and Food Board
core   +1 more source

TRACESS OF ALUMINIUM IN RAW MILK AND THE EFFECT OF BOILING OF MILK AND STORAGE IN THE ALUMINIUM UTENSILS

Assiut Veterinary Medical Journal, 2009
  The level of aluminium was evaluated in raw milk sold in markets and the effect of Kitchen aluminium utensils on aluminium content of milk during boiling and storing at 4oC for different periods, the amount of aluminium was determined by atomic ...
EMAN I. EL-MOSSALAMI, SHIREEN M. NOSEIR
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source