Results 31 to 40 of about 908,626 (266)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A pioneering genotypic and phylogenetic characterisation of Cichorium crops through a genome-scale sequencing for future breeding innovations

open access: yesBMC Plant Biology
The genus Cichorium, which comprises economically important crops such as chicory and endive, exhibits significant genetic and phenotypic diversity. This study used genome-scale sequencing based on ddRAD technology to explore the genetic diversity and ...
Francesco Scariolo   +7 more
doaj   +1 more source

The History of the School of Animal Science at the University of Padova (Padua) and the Evolution of Animal Science in Italy

open access: yesAgriculture, 2022
In its 800-year history, the University of Padova (Padua, Italy) has come to play an important role in the development of animal science in Italy and Europe.
Giovanni Bittante   +8 more
doaj   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Effect of dietary supplementation with purified wood lignocellulose on performances, caecal fermentation and gut microbiota of growing rabbits

open access: yesItalian Journal of Animal Science
A total of 576 rabbits were housed in 18 open-top elevated pens (32 rabbits per pen) during the fattening period (54–71 d of age) and fed a standard diet or a diet enriched in purified wood lignocellulose and fat formulated to guarantee rabbit optimal ...
Giulia Zardinoni   +7 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Growth performance and carcass traits of growing and finishing pigs fed diets with a partial to total replacement of soybean meal with Spirulina powder

open access: yesJournal of Animal Science and Biotechnology
Background The protein sources in pig diets strongly rely on soybean meal, but its production has been associated with soil degradation, deforestation and loss of biodiversity.
Gregorio Don   +4 more
doaj   +1 more source

Short-term climate change effects on maize phenological phases in northeast Italy

open access: yesItalian Journal of Agronomy, 2019
This study evaluates the response of maize growing cycle length to meteorological variables at regional scale particularly, in the short-term period, considering global climate change.
Antonio Berti   +3 more
doaj   +1 more source

How animal milk and plant-based alternatives diverge in terms of fatty acid, amino acid, and mineral composition

open access: yesnpj Science of Food, 2023
The decline in fresh milk in the Western world has in part been substituted by an increased consumption of plant-based beverages (PBB). These are often marketed as healthy and sustainable alternatives to milk and dairy foodstuff, although studies have ...
S. S. Moore   +6 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

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