Results 91 to 100 of about 1,856,984 (314)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Scientific Opinion on nitrofurans and their metabolites in food

open access: yesEFSA Journal, 2015
Nitrofurans are antimicrobial agents not authorised for use in food‐producing animals in the European Union. Nitrofurans are rapidly metabolised, occurring in animal tissues as protein‐bound metabolites.
EFSA Panel on Contaminants in the Food Chain (CONTAM)
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Scientific Opinion on the abiotic risks for public and animal health of glycerine as co‐product from the biodiesel production from Category 1 animal by‐products (ABP) and vegetable oils

open access: yesEFSA Journal, 2010
Following a request from the European Commission, the European Food Safety Authority (EFSA) was asked to deliver a scientific opinion on the abiotic risks for public and animal health of glycerine as co‐product from the biodiesel production from Category
EFSA Panel on Contaminants in the Food Chain (CONTAM)
doaj   +1 more source

WHO IS MOST RESPONSIBLE FOR ENSURING THE MEAT WE EAT IS SAFE? [PDF]

open access: yes
We report results of an analysis of the attribution of relative responsibility across the stages of the food chain for ensuring food safety. Specifically, we identify perceptions of the share of the overall responsibility that each stage in the food ...
Erdem, Seda, Rigby, Dan, Wossink, Ada
core   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

Statement on possible public health risks for infants and young children from the presence of nitrates in leafy vegetables

open access: yesEFSA Journal, 2010
Nitrate is a naturally occurring compound present in vegetables, the consumption of which can contribute significantly to nitrate dietary exposure.
EFSA Panel on Contaminants in the Food Chain (CONTAM)
doaj   +1 more source

Chain Management: All about Success [PDF]

open access: yes
Nowadays food products are produced in vertically collaborating networks. The questions of how such chain networks have to be designed and which governance structure fits best have been addressed in several well known articles. However, questions dealing
Gagalyuk, Taras, Hanf, Jon Henrich
core   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Scientific Opinion on marine biotoxins in shellfish – Emerging toxins: Brevetoxin group

open access: yesEFSA Journal, 2010
The EFSA Panel on Contaminants in the Food Chain (CONTAM Panel) assessed the risks to human health related to the consumption of brevetoxin‐(BTX) group toxins in shellfish and fish.
EFSA Panel on Contaminants in the Food Chain (CONTAM)
doaj   +1 more source

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