Results 321 to 330 of about 6,134,549 (389)

Decoding Hydrogel Porosity: Advancing the Structural Analysis of Hydrogels for Biomedical Applications

open access: yesAdvanced Healthcare Materials, EarlyView.
Porosity governs transport mechanics in hydrogels, yet characterization in its native state remains challenging. This work harnesses particle tracking to uncover three‐dimensional pore geometric features in polyethylene glycol hydrogels. Measurements in the native state reveal pores characteristics are comparable to those obtained by cryogenic scanning
M. A. Kristine Tolentino   +5 more
wiley   +1 more source

Engineered MSC Aggregates with E/N‐Cadherin and IL‐6 Preconditioning for the Treatment of Systemic Sclerosis

open access: yesAdvanced Healthcare Materials, EarlyView.
Engineered 3D‐Cad/IL6‐MSC, developed through synergistic hE/N‐cad‐Fc and IL‐6 preconditioning, show remarkable therapeutic potential for systemic sclerosis. These engineered MSC aggregates reduce pathogenic inflammatory cell infiltration and restore immune balance among CD4+ T‐cell populations, offering a promising approach to optimize MSC based ...
Yue Zhang   +11 more
wiley   +1 more source

Chain of Cold Food

open access: yesJournal of Microbiology & Experimentation, 2017
openaire   +2 more sources

Animal‐Free Setup of a 3D Mature Adipocyte‐Macrophage Co‐Culture to Induce Inflammation In Vitro

open access: yesAdvanced Healthcare Materials, EarlyView.
A completely animal‐free 3D co‐culture is developed using human fat cells and immune cells. Animal‐based materials are replaced with gellan gum hydrogel and a serum‐free medium. Immune cells are effectively activated, producing specific inflammatory signals.
Sophia Nowakowski   +3 more
wiley   +1 more source

Permeation Enhancer‐based Ionogel Shows Remarkable Potential for Oral Insulin Delivery

open access: yesAdvanced Healthcare Materials, EarlyView.
This study proposes a novel formulation of decanoate in an ionic liquid inspired drug delivery system. The formulation demonstrates ideal physicochemical and material properties for oral peptide delivery. Findings indicate that choline decanoate (1:2 molar ratio) forms a viscoelastic gel that enables high oral bioavailability of insulin in rats ...
Konstantinos Raptis   +6 more
wiley   +1 more source

Dissolving Microneedle for Maintaining the Integrity of HPV Virus‐Like Particles Enabling Durable Sterile Protection Across Various Mucosal Tissues

open access: yesAdvanced Healthcare Materials, EarlyView.
A novel dissolving microneedle platform preserves HPV virus‐like particle (VLP) immunogenicity by maintaining structural integrity, crucial for eliciting potent immune responses. Buccal administration induces robust immune response, high neutralizing antibody titers, and durable sterile protection across oral and vaginal mucosal sites.
Hyemi Kim   +12 more
wiley   +1 more source

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