Results 91 to 100 of about 4,331,785 (249)

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Exploring food choices among educated adults in the United Arab Emirates

Frontiers in Nutrition
IntroductionUnderstanding food choice motives (FCMs) is crucial to designing dietary interventions to improve human health and environmental sustainability.
Souzan Zidan, Serene Hilary, Carine Platat, Carine Platat   +3 more
doaj   +1 more source

Factors of Purchase of Bread – Prospect to Regain the Market Share?

Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2016
The aim of the article is to assess the consumers’ buying behaviour and decision-making process when purchasing bread and to propose the ways of how to improve the position of bread in the market.
Ladislav Skořepa, Kamil Pícha
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Social learning in bonobos: Learning of individual food preferences and copying despite better knowledge

Revue de Primatologie, 2015
Over the past few decades there has been a growing interest into social learning in animals. The importance of social influence on food choice has been demonstrated across a number of species including humans.
Gladez Shorland, Emilie Genty, Klaus Zuberbühler   +2 more
doaj   +1 more source

Determinants of Choice Regarding Food with Nutrition and Health Claims [PDF]

Health is an increasingly important topic in the food market. The regulation (EC) No 1924/2006 on nutrition and health claims is meant to facilitate healthy food choices of consumers.
Hamm, Ulrich, Aschemann, J.
core  

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Temptation at the school fence: a qualitative exploration of the impact of external food outlets on the school community

BMC Public Health
Retail food outlets are commonly located in close proximity to schools, providing students with opportunities to purchase and consume food enroute to or from school. These outlets are typically unhealthy and disproportionately clustered near schools, and
Sharonna Mossenson, Frith Klug, Jacinta Francis, Siobhan Hickling, Lukar Thornton, Gina Trapp   +5 more
doaj   +1 more source

Drivers of Food Decision Making and Aspirations for the Future of the School Food Environment among Junior High School Students in Cape Coast, Ghana: a Photovoice Study

Current Developments in Nutrition
Background: Food decision making is a complex and dynamic process that influences diet and ultimately health. Adolescents consider many different food environment-level factors when making decisions about food.
Elise C Reynolds, Christiana Nsiah-Asamoah, Harriet Okronipa, Nicholas F Russell, Madina Habib, Christine P Stewart   +5 more
doaj   +1 more source

Gender Differences in Food Choice: Effects of Superior Temporal Sulcus Stimulation

Frontiers in Human Neuroscience, 2017
The easy availability of food has caused a shift from eating for survival to hedonic eating. Women, compared to men, have shown to respond differently to food cues in the environment on a behavioral and a neural level, in particular to energy rich ...
Valerio Manippa, Caterina Padulo, Laura N. van der Laan, Alfredo Brancucci   +3 more
doaj   +1 more source