Results 71 to 80 of about 2,423,033 (311)
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Food Insecurity, ICT, and Food Culture Mismatch [PDF]
Ecology of Food and Nutrition (EFN) promotes scholarly discussion and engagement on the holistic and cross-cultural dimensions of the study of food and nutrition.
openaire +2 more sources
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Bivalve mollusc culture research in Thailand [PDF]
An account of research, which explored new biological and socioeconomic perspectives on bivalve mollusc culture to increase production and to improve the livelihood of farmers.
Chongpeepien, T. (eds.), McCoy, E.W.
core
The Obesity of Economics: An Application of the Law of Demand to Obesity Prevalence within the United States [PDF]
We estimate the demand function for obesity using a panel model across fifty-one U.S. states over the years 2000 to 2010. We study the impact of educational attainment, average commute time to work, relative price, per capita income, and the state ...
Hasenoehrl, Amy, Hill, Tara Marie
core +1 more source
The translation of food-related culture-specific items in the COVALT corpus: A study of techniques and factors [PDF]
This article aims to analyse the translation of food-related culturespecific items (CSI) in the English–Catalan subcorpus of the Valencian Corpus of Translated Literature (COVALT). This general aim can be broken down into two specific aims: to find out
Marco, Josep
core +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
The Rise and Fall of the Jumbo Breakfast Roll: How a Sandwich Survived the Decline of the Irish Economy [PDF]
This paper examines a specific food item - the Jumbo Breakfast Roll [JBR] - through a sociological lens, in order to trace the factors that contributed to its rise to prominence in Irish food culture in the 'Celtic Tiger' period of the late 20th/early ...
Perry Share
core
Sun of Justice Rising: Tonatierra Community Development Institute [PDF]
Salvador Reza, a longtime organizer for indigenous Mexican rights, helped lead a successful campaign to organize taco vendors in Phoenix. Faced with a local ordinance that would restrict the operation of mobile food stands, effectively banning them, Reza
David Gomez +4 more
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