Results 71 to 80 of about 2,822,776 (281)
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Applied SciencesThis study examines the link between food deserts and cardiovascular health in older adults in Santiago’s Metropolitan Region, Chile. As the population ages and chronic diseases rise, understanding the impact of food accessibility on health is essential.
Leslie Landaeta-Díaz +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
Identifying Food Deserts in Mississauga: A Comparative Analysis of Socioeconomic Indicators
Urban ScienceA lack of access to healthy food has been a problem for low-income residents in many developed urban areas. Due to travel time and additional transportation costs, these residents often opt for unhealthy food rather than nutritious alternatives.
Taif Huda +5 more
doaj +1 more source
Food Deserts: How Little, Fresh Food Results in Large Problems [PDF]
, 2020 This presentation and paper talk focuses on food deserts and the role it plays in communities. The term food desert is defined due to its qualities and characteristics. The effects of food deserts are addressed.
Tobia, Keira
core
The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity
FEBS Open Bio, EarlyView.Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav +4 more
wiley +1 more source
Urban PlanningFood deserts highlight the uneven distribution of food infrastructure that disproportionately impacts marginalised communities, exacerbating their food insecurity.
Francisco García, Rita Lambert
doaj +1 more source
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
FEBS Open Bio, EarlyView.To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
, 2020 Informing about what food deserts in America are and why they are important in hopes to get the word out about them and help solve this ...
Kelly, Linden
core +1 more source
Journal of Public Health Research, 2014 Background. This ecological study examines the relationship between food desert prevalence and academic achievement at the school district level. Design and methods. Sample included 232 suburban and urban school districts in New York State. Multiple open-
Seth E. Frndak
doaj +1 more source