Results 111 to 120 of about 4,794,869 (310)

Pharmacokinetics of the evogliptin/metformin extended-release (5/1,000 mg) fixed-dose combination formulation compared to the corresponding loose combination, and food effect in healthy subjects

open access: yesDrug Design, Development and Therapy, 2016
Su-jin Rhee,1,* SeungHwan Lee,1,2,* Seo Hyun Yoon,1 Joo-Youn Cho,1 In-Jin Jang,1 Kyung-Sang Yu1 1Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, 2Clinical Trials Center, Seoul National ...
Rhee SJ   +5 more
doaj  

Buyer Power and Product Innovation: Empirical Evidence from the German Food Sector. [PDF]

open access: yes
Substantial increases in retail concentration (particularly in Europe) raise concerns about the welfare implications for consumers. In a formal model, we argue that retailer market power reduces upstream firms incentives to introduce new products. On the
Weiss, Christoph R., Wittkopp, Antje
core  

No. 15: The Food Security Implications of Gendered Access to Education and Employment in Maputo [PDF]

open access: yes, 2018
The multiple linkages between gender and household food security in cities have been observed in diverse settings, at multiple scales, and through a variety of disciplinary lenses.
McCordic, Cameron   +2 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Examining the Effect of SES on Access to Nutritional Food [PDF]

open access: yes, 2012
America has recently seen an increasing epidemic of diet related diseases in people of all backgrounds. However, the brunt of these health risks, especially those stemming from obesity, seem to disproportionately fall on those of lower socioeconomic ...
White, Rebecca
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Genotype moderates the impact of food additives on hyperactive behavior in children

open access: yes, 2007
Introduction: The claim of a relationship between artificial food color and additive (AFCs) intake and behavior is highly contentious. We have shown in a previous population-based trial with 3yo children adverse effects of food additives on parentally ...
Grimshaw, K.E.C.   +5 more
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Measuring Food Security for Pakistan Using 2007-08 HIES Data [PDF]

open access: yes
Food is one of the most basic rights of every one living on this earth to get food. Food insecurity has very serious consequences in term of undermining people’s health, productivity and even their very survival.
Asghar, Zahid
core   +1 more source

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