Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Learning our way towards a sustainable agri-food system Three cases from Sweden: Stockholm Farmers market, Ramsjö Community Supported Agriculture and Järna Initiative for Local Production [PDF]
, 2003 This research is based on case studies of the Stockholm Farmers Market, Ramsjö Community Supported Agriculture, and Järna Initiative for Local Production. These cases are examples of alternative consumerproducer links in the Swedish agri-food system.
Adler, Steffen +3 more
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The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential
Aging and Cancer, EarlyView.As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley +1 more source
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham +7 more
wiley +1 more source
Students and Healthy Eating: The Behavior–Intention Gap in an Unhealthy Food Environment
ProceedingsBackground and objectives: Our food environment has a large influence on what we eat. The food environment around five schools in ‘Education Boulevard’ in the city of ‘s-Hertogenbosch (The Netherlands) is not healthy.
Amely Verreijen +2 more
doaj +1 more source
INVESTIGATION OF PHYTOINDICATION EFFECTS DUE TO CADMIUM CONTAMINATION [PDF]
, 2018 Heavy metals are one of the most dangerous contaminants in the natural environment that cause toxic effects in the cells of plants and animals. They are not decomposed in the environment but consequently accumulated in the tissues of living organisms.
Kovrov, Oleksandr, Tsunik, Ksenia
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Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon +12 more
wiley +1 more source
Improving Child Nutrition Policy: Insights From National USDA Study of School Food Environments [PDF]
, 2009 Highlights findings from the 2004-05 School Nutrition Dietary Assessment Study on the food environment in public schools and links to obesity.
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