Results 81 to 90 of about 3,423,826 (360)

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Repeated biocide treatments cause changes to the microbiome of a food industry floor drain biofilm model

Frontiers in Microbiology
There is a concern about the development of microbial tolerance and resistance to biocides due to their repeated use within the food industry. This study aimed to develop a floor drain biofilm model and test whether repeated biocide treatment would ...
Martin Laage Kragh, Nanna Hulbæk Scheel, Pimlapas Leekitcharoenphon, Lisbeth Truelstrup Hansen   +3 more
doaj   +1 more source

Local Food Impacts on Health and Nutrition [PDF]

Prevalence of local foods is believed to answer several food issues one of which is health and nutrition. This study focused on the on the availability of local foods to consumers and see its relationship with two specific diet-related diseases namely ...
Escalante, Cesar L., Ferrer, Myra Clarisse R., Fonsah, Esendugue Greg, Ramirez, Octavio A.   +3 more
core   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

A Roadmap to Reduce U.S. Food Waste By 20 Percent, Executive Summary 2016 [PDF]

, 2016
The magnitude of the food waste problem is difficult to comprehend. The U.S. spends $218 billion a year -- 1.3% of GDP -- growing, processing, transporting, and disposing of food that is never eaten.

core  

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

The effectiveness, cost-effectiveness and policy processes of regulatory, voluntary and partnership policies to improve food environments: an evidence synthesis

Public Health Research
Background Dietary factors are among the largest and costliest drivers of chronic diseases in England. As a response, the government implements a range of population interventions to promote healthy diets by targeting food environments.
Laurence Blanchard, Stephanie Ray, Cherry Law, María Jesús Vega-Salas, Julia Bidonde, Gemma Bridge, Matt Egan, Mark Petticrew, Harry Rutter, Cécile Knai   +9 more
doaj   +1 more source

Long-term Impact of sewage sludge application on rhizobium leguminosarum biovar trifolii: an evaluation using meta-analysis [PDF]

, 2016
The Long-Term Sludge Experiment (LTSE) began in 1994 at nine UK field sites as part of continuing research into the effects of sludge-borne heavy metals on soil fertility. The long-term effects of Zn, Cu, and Cd on the most probable numbers of cells (MPN)
Alex Charlton, Alloway, Berrow, Borenstein, Borenstein, Broos, CEC, Chaudri, Chaudri, Chaudri, Chaudri, Colin D. Campbell, Department for Environment, Food and Rural Affairs, Department for Environment, Food and Rural Affairs, Gendebien, Gendebien, Gibbs, Giller, Giller, Giller, Giller, Hedges, Hedges, Hedges, Hedges, McBride, McBride, McGrath, McGrath, McGrath, McGrath, Ministry of Agriculture, Fisheries and Food, Ministry of Agriculture, Fisheries and Food, Renella, Ruben Sakrabani, Smith, Steve P. McGrath, Thornton, UK Water Industry Research Limited, UK Water Industry Research Limited, Vincent, Water UK, Witter, Woomer   +43 more
core   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Food purchase diversity is associated with market food diversity and diets of children and their mothers but not fathers in rural Tanzania: Results from the EFFECTS baseline survey

Maternal and Child Nutrition
Rural households in East Africa rely on local markets, but the influence of market food diversity and household food purchase diversity on diets has not been well‐characterized.
Savannah F. O'Malley, Ramya Ambikapathi, Morgan Boncyk, Dominic Mosha, Cristiana K. Verissimo, Lauren Galvin, Frank Mapendo, Isaac Lyatuu, Mary Pat Kieffer, Joshua Jeong, Evidence Matangi, George PrayGod, Nilupa S. Gunaratna   +12 more
doaj   +1 more source