Results 61 to 70 of about 3,446,498 (308)
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
An Investigation of the Environmental Turbulence Factors and their Sources in the Collaboration - Post-harvest Food Loss Relationship [PDF]
, 2015 Recent studies suggested that collaboration among upstream agricultural supply chain (ASC) partners will impact and possibly reduce postharvest food loss (PHFL) levels; a possible direct relationship between collaboration and PHFL was indicated.
Dani, Samir +2 more
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Food choice by people with intellectual disabilities at day centres: A qualitative study [PDF]
, 2014 People with intellectual disabilities experience a range of health inequalities. It is important to investigate possible contributory factors that may lead to these inequalities.
Blackburn, Chrissie +4 more
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
A Roadmap to Reduce U.S. Food Waste By 20 Percent, Executive Summary 2016 [PDF]
, 2016 The magnitude of the food waste problem is difficult to comprehend. The U.S. spends $218 billion a year -- 1.3% of GDP -- growing, processing, transporting, and disposing of food that is never eaten.
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Food Environment, Food Store Access, Consumer Behavior, and Diet [PDF]
Food Environment, Food Deserts, Obesity, Consumer Behavior, Diet, Food Consumption/Nutrition/Food Safety, I18, R50,
Ver Ploeg, Michele
core +1 more source
No. 10: The Hungry Cities Food Purchases Matrix: A Measure of Urban Household Food Security and Food System Interactions [PDF]
, 2017 Recent theoretical work has suggested that urban food security is the result of food system interactions. This work highlights the challenge of assessing household-level food insecurity and relating it to the broader food system.
Crush, Jonathan, McCordic, Cameron
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source