Results 41 to 50 of about 3,446,498 (308)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Food environment around schools and adolescent consumption of unhealthy foods in Addis Ababa, Ethiopia

open access: yesMaternal and Child Nutrition
Adolescent diets may be influenced by the retail food environment around schools. However, international research to examine associations between the proximity of retail food outlets to schools and diet provides equivocal support for an association. This
Hanna Y. Berhane   +5 more
doaj   +1 more source

The role of Australian local governments in creating a healthy food environment: an analysis of policy documents from six Sydney local governments

open access: yesAustralian and New Zealand Journal of Public Health, 2020
Objective: This paper examines policies from six local governments (LGs) relevant to promoting a healthy food supply and consumer food environment. Methods: We analysed the six LGs’ food and nutrition policies against a framework based on Australian ...
Belinda Reeve   +4 more
doaj   +1 more source

Factors affecting fruit and vegetable consumption and purchase behavior of adults in sub-Saharan Africa: A rapid review

open access: yesFrontiers in Nutrition, 2023
In order to achieve the Sustainable Development Goals, considerable dietary shifts, including an increase in the consumption of fruit and vegetables (FV) will be required.
Barbara Stadlmayr   +11 more
doaj   +1 more source

Consumer food environment and overweight

open access: yesNutrition, 2019
The aim of this study was to investigate the association between aspects of the consumer food environment in food stores selling fruit and vegetables (FVs) and the incidence of overweight among users of a Brazilian primary health care service.This cross-sectional study assessed individual-level and food environment variables, within the context of a ...
Patrícia Pinheiro, de Freitas   +2 more
openaire   +2 more sources

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Development of non-sweet, flavored food cubes [PDF]

open access: yes, 1971
Food cubes exhibit flavor and quality stability for periods of four weeks in 100 deg F environment. They are suitable for field rations, emergency rations or snacks and should interest the food processing ...
Larson, R. W.
core   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Food Environment, Built Environment, and Women\u27s BMI: Evidence from Erie County, New York [PDF]

open access: yes, 2010
The authors present the results of a neighborhood-scaled exploratory study that tests the association of the food environment and the built environment with women’s body mass index (BMI) in Erie County, New York.
Alex Brian Ticoalu   +6 more
core   +1 more source

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