Results 321 to 330 of about 5,227,768 (412)

A Novel Core–Shell Hydrogel 3D Model for Studying Macrophage Mechanosensing and Foreign Body Giant Cell Formation

Advanced Healthcare Materials, EarlyView.
The foreign body response (FBR) to biomaterials is primarily driven by macrophages, which often fuse into destructive foreign body giant cells (FBGCs). To address the limited understanding of FBGC formation, a novel microscale core–shell hydrogel 3D model is developed using heterogeneous alginate‐collagen microcapsules with varying stiffness, offering ...
Manisha Mahanty, Wenquan Ou, Xiaoping Zhu, Jonathan S Bromberg, Xiaoming He, Shaik O. Rahaman   +5 more
wiley   +1 more source

Safety evaluation of the food enzyme acetolactate decarboxylase from the genetically modified <i>Bacillus subtilis</i> strain DP-Ezz65. [PDF]

EFSA J
EFSA Panel on Food Enzymes (FEZ), Zorn H, Barat Baviera JM, Bolognesi C, Catania F, Gadermaier G, Greiner R, Mayo B, Mortensen A, Roos YH, L M Solano M, Sramkova M, Van Loveren H, Vernis L, Andryszkiewicz M, Cavanna D, Fernàndez-Fraguas C, Peluso S, Liu Y.   +18 more
europepmc   +1 more source

Xeno‐Free Biocompatible Peptide‐Based Bioinks Reinforced with Cellulose Nanofibers for 3D Printing

Advanced Healthcare Materials, EarlyView.
A xeno‐free bioink combining self‐assembled peptides and cellulose nanofibers is developed for 3D printing. The bioink forms a non‐cross‐linked 3D scaffold, mimicking the extracellular matrix and supporting over 95% cell viability. This approach offers enhanced biocompatibility and mechanical stability, advancing 3D printing for personalized medicine ...
Francesca Netti, Mor Tsuriano, Noam Rattner, Vania Altobelli, Yoav Dan, Lihi Adler‐Abramovich   +5 more
wiley   +1 more source

Safety evaluation of the food enzyme prolyl oligopeptidase from the genetically modified <i>Trichoderma reesei</i> strain DP-Nyq99. [PDF]

EFSA J
EFSA Panel on Food Enzymes (FEZ), Zorn H, Barat Baviera JM, Bolognesi C, Catania F, Gadermaier G, Greiner R, Mayo B, Mortensen A, Roos YH, Solano MLM, Sramkova M, Van Loveren H, Vernis L, Aguilera J, Cavanna D, Fernàndez-Fraguas C, Kovalkovicova N, Lunardi S, Liu Y.   +19 more
europepmc   +1 more source

Decellularized Extracellular Matrix Scaffolds to Engineer the Dormant Landscape of Microscopic Colorectal Cancer Liver Metastasis

Advanced Healthcare Materials, EarlyView.
Decellularized liver extracellular matrix scaffolds provide a platform to study dormant liver‐metastatic colorectal cancer. They induce reversible dormancy, in combination with nutrient depletion and low dose chemotherapy, through cell cycle arrest and chemotherapy resistance.
Sabrina N. VandenHeuvel, Lucia L. Nash, Abigail J. Clevenger, Claudia A. Collier, Oscar R. Benavides, Sanjana Roy, Brinlee Goggans, Aelita Salikhova, Anvitha Tharakesh, Svasti Haricharan, Amber N. Stratman, Scott Kopetz, Alex J. Walsh, Shreya A. Raghavan   +13 more
wiley   +1 more source

Safety evaluation of the food enzyme glucose oxidase from the non-genetically modified <i>Penicillium rubens</i> strain PGO 19-162. [PDF]

EFSA J
EFSA Panel on Food Enzymes (FEZ), Zorn H, Barat Baviera JM, Bolognesi C, Catania F, Gadermaier G, Greiner R, Mayo B, Mortensen A, Roos YH, Solano MLM, Sramkova M, Van Loveren H, Vernis L, Criado A, Aguilera J, Fernández-Fraguas C, Andryszkiewicz M, Sanmartin L, Liu Y.   +19 more
europepmc   +1 more source

Multiscale Profiling of Nanoscale Metal‐Organic Framework Biocompatibility and Immune Interactions

Advanced Healthcare Materials, EarlyView.
A multi‐scale, hierarchical ‘Safety‐by‐Design’ pipeline combining machine learning, ex vivo human blood assays, and in vivo models enables the systematic immunotoxicity and biocompatibility profiling of nanoscale metal‐organic frameworks, accelerating their safe clinical translation. Abstract The clinical translation of metal‐organic frameworks (MOFs) –
Yunhui Zhuang, Bárbara B. Mendes, Dhruv Menon, Jhenifer Oliveira, Xu Chen, Fatma Demir Duman, João Conniot, Sergio Mercado, Xiewen Liu, Shi‐Yuan Zhang, João Conde, Rachel E. Hewitt, David Fairen‐Jimenez   +12 more
wiley   +1 more source

Safety evaluation of the food enzyme endo-1,4-β-xylanase from the genetically modified <i>Trichoderma reesei</i> strain DP-Nzd72. [PDF]

EFSA J
EFSA Panel on Food Enzymes (FEZ), Zorn H, Barat Baviera JM, Bolognesi C, Catania F, Gadermaier G, Greiner R, Mayo B, Mortensen A, Roos YH, Solano MLM, Sramkova M, Van Loveren H, Vernis L, Cavanna D, Criado A, Fernández-Fraguas C, Lunardi S, Tokić V, Liu Y.   +19 more
europepmc   +1 more source

ROS‐Scavenging Multifunctional Microneedle Patch Facilitating Wound Healing

Advanced Healthcare Materials, EarlyView.
A reactive oxygen species (ROS) scavenging and immunomodulatory microneedle patch based on hyaluronic acid methacrylate (HaMA) and Flightless I (Flii)‐siRNA‐laden arginine functionalized poly (β‐amino ester)/alginate particles is developed for chronic wound healing applications.
Mahshid Kharaziha, Sahar Salehi, Mahshid Shokri, Seyed Mohsen Ahmadi Tafti, Thomas Scheibel   +4 more
wiley   +1 more source

Safety evaluation of an extension of use of the food enzyme endo-polygalacturonase from the genetically modified <i>Trichoderma reesei</i> strain RF6197. [PDF]

EFSA J
EFSA Panel on Food Enzymes (FEZ), Zorn H, Barat Baviera JM, Bolognesi C, Catania F, Gadermaier G, Greiner R, Mayo B, Mortensen A, Roos YH, Solano MLM, Sramkova M, Van Loveren H, Vernis L, Pasch J, Liu Y.   +15 more
europepmc   +1 more source