Results 31 to 40 of about 47,916 (257)
Social entrepreneurship in agri-food systems: the case of food hubs
Abstract Food hubs are nascent organizational innovations in local and regional food systems. Although the number of food hubs in the U.S. has grown over the past decade, their purpose in the food system is still debated. There is a lack of clarity in whether food hubs primarily pursue a social mission, economic value creation, or both simultaneously ...
Tatevik Avetisyan +2 more
openaire +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Comparative genomics of the highly halophilic Haloferacaceae
The Haloferacaceae are a family of extremely halophilic archaea with many species producing enzymes and products beneficial for industrial biotechnology. They are, however, relatively under-characterised with regards to genetics and gene products.
Dana B. Griffiths +3 more
doaj +1 more source
This research builds a mathematical modelling to assess food waste production when designing sustainable packaging solutions integrated with an agricultural intervention in kale production.
Francesco S. Giordano +4 more
doaj +1 more source
The research analyzed the impact of the Rural Enterprise Development Hub Project (RED Hub Project) on food security of maize farmers. The data were analyzed using both inferential and descriptive statistics.
Enoch Terlumun Iortyom +2 more
doaj +1 more source
Food hubs create a range of economic, social, and environmental impacts through a wide variety of activities and programs. Evaluation of these impacts is important; however, many hubs lack the capacity (including time, resources, knowledge, and expertise) to do effective, ongoing evaluation work.
Erin Nelson, Karen Landman
openaire +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
AGROVOC: The linked data concept hub for food and agriculture
Newly acquired, aggregated and shared data are essential for innovation in food and agriculture to improve the discoverability of research. Since the early 1980′s, the Food and Agriculture Organization of the United Nations (FAO) has coordinated AGROVOC, a valuable tool for data to be classified homogeneously, facilitating interoperability and reuse ...
Imma Subirats Coll +6 more
openaire +2 more sources
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source

