Results 41 to 50 of about 19,538,269 (287)

Challenges, opportunities, and future perspectives of food safety risk communication in the era of algorithmic recommendation

open access: yesZhongguo shipin weisheng zazhi
Risk communication is an important component of food safety management. Effective risk communication facilitates enhanced food safety risk management and promotes public health.
RUAN Guangfeng   +3 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Which Messages about Healthy and Sustainable Eating Resonate Best with Consumers of Low Socio-Economic Status?

open access: yesProceedings
Consumers of low socio-economic status (SES) face unique challenges in eating healthily and sustainably, and as a result, are disproportionately affected by the greater risks of chronic diseases and environmental degradation.
Aikaterini Palascha   +2 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Information and food blogging as serious leisure [PDF]

open access: yesAslib Proceedings, 2011
PurposeThe purpose of this paper is to explore aspects of creating, seeking, sharing and management of information in food blogging as serious leisure.Design/methodology/approachParticipants' conceptualisation of food blogging and the role of information in it is interpreted through in‐depth interviews and analysis of activity on the UK Food Bloggers ...
Andrew M. Cox 0001, Megan K. Blake
openaire   +2 more sources

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Informalized containment: food markets and the governance of the informal food sector in Windhoek, Namibia [PDF]

open access: yesEnvironment and Urbanization, 2019
Policy responses to the growth of the informal food sector in African cities vary from benign neglect to active destruction. The eradication of street food vending is the dominant mode of governance. Alternative approaches that recognize the inevitability of informality and the role of the sector in making food accessible to the urban poor have begun ...
Lawrence N Kazembe   +2 more
openaire   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Comparative analysis of dynamic models describing of the process dynamics of acetic acid fermentation [PDF]

open access: yesBIO Web of Conferences
This paper presents a comparative analysis of kinetic models describing the dynamics of the acetic acid fermentation process in continuous operation. For this purpose, simulation structural models were implemented, a calculation was made of the values of
Sestrimska Mariyana   +2 more
doaj   +1 more source

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