Results 251 to 260 of about 3,238,550 (370)
Abstract In human health risk assessment of chemicals and pharmaceuticals, identification of genotoxicity hazard usually starts with a standard battery of in vitro genotoxicity tests, which is needed to cover all genotoxicity endpoints. The individual tests included in the battery are not designed to pick up all endpoints.
Mirjam Luijten +15 more
wiley +1 more source
Engineered food-borne probiotics delivering checkpoint-inhibitor modulators. [PDF]
Mehmood MS, Masood M, Danaf N.
europepmc +1 more source
Microbiology of Sandwiches: “Street – Foods” and “Fast – Foods”
Ana Cláudia Chesca +2 more
openalex +2 more sources
Abstract Gene expression biomarkers have the potential to identify genotoxic and non‐genotoxic carcinogens, providing opportunities for integrated testing and reducing animal use. In August 2022, an International Workshops on Genotoxicity Testing (IWGT) workshop was held to critically review current methods to identify genotoxicants using ...
Roland Froetschl +14 more
wiley +1 more source
Review of Transcriptomic Biomarkers That Predict In Vitro Genotoxicity in Human Cell Lines
ABSTRACT The current genotoxicity testing paradigm provides little mechanistic information, has poor specificity in predicting carcinogenicity in humans, and is not suited to assessing a large number of chemicals. Genomic technologies enable the characterization of genome‐wide transcriptional changes in response to chemical treatments that can inform ...
Heng‐Hong Li +7 more
wiley +1 more source
Abstract As one of the most abundant renewable resources and complex aromatic polymers, lignin holds great promise for producing monophenolic compounds. However, its depolymerization into valuable monomers is hindered by intricate side reactions. In this study, alkaline lignin was converted into vanillin using nine choline chloride‐based deep eutectic ...
Xiaoyan Chen, Xiaohui Pan, Dongyang Cui
wiley +1 more source
Training in tools and modelling to develop risk ranking and quantitative microbial risk assessment for cheese along the Polish and Spanish food. [PDF]
Sęczkowska O +4 more
europepmc +1 more source
Equine trypanosomiasis, a systematic review: Disease management
Abstract Background Equine trypanosomiasis is a neglected protozoal disease. Objectives To answer the study question: In equines what are the effects of disease management of trypanosomiasis on disease severity (individual level) and disease prevalence (population level) compared to no intervention? Study Design Systematic review.
Alexandra G. Raftery +5 more
wiley +1 more source

