Results 101 to 110 of about 1,340,793 (315)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Small Farm Food Safety, Fresh Produce: Part 1: Introduction to the PACE Principles

open access: yesEDIS, 2007
FCS8842, a factsheet by Brian Lapinski, Amy Simonne, and M.E. Swisher, introduces readers to the PACE principles (prevention, accountability, control, and education) of food safety as they apply to small farm management.
Brian Lapinski   +2 more
doaj   +1 more source

ECONOMIC EFFECTS OF CO-EXISTENCE MEASURES IN MAIZE CROP AND SEED PRODUCTION - A CASE STUDY OF FRANCE [PDF]

open access: yes
Paper prepared for presentation at the Second International Conference on Coexistence between Genetically Modified (GM) and non-GM based Agricultural Supply Chains (GMCC) Montpellier (France), 14th and 15th November 2005Genetic engineering, GMO, Maize ...
Angevin, F.   +5 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Presentation of results using the BOST method in food industry

open access: yesProduction Engineering Archives, 2014
This paper presents a brief description of the surveyed enterprises and the manufacturing process of its flagship product - butter. Subsequently an analysis of BOST survey results was conducted.
Stanisław Borkowski, Kamila Adamus
doaj  

Evaluation of policy measures for agri-food networks in Italian rural development programmes [PDF]

open access: yes
The agri-food sector is characterized by very heterogeneous agreements and formal and informal contracts aimed to create stable relationships among firms. In this scenario, the actors are linked by common interest in creating and distributing added value.
Berletti, Maria   +3 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

The New Global Context for Agricultural Research - Implications for Policy [PDF]

open access: yes, 1986
Presentation on the world food situation to the CGIAR meeting in October-November 1986 by the Director of IFPRI, John Mellor. This was the second such, following a recommendation by the first external review of IFPRI that the Institute's director should ...
International Food Policy Research Institute   +1 more
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Home - About - Disclaimer - Privacy