Results 91 to 100 of about 2,058,396 (312)
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to evaluate a flavouring substance in the Flavouring Group Evaluation 300 using the Procedure in Commission Regulation (EC ...
EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF)
doaj +1 more source
Analysis of the Economic Effects of Requiring Post-harvest Processing for Raw Oysters [PDF]
oysters, post-harvest processing, hydrostatic pressure, cool pasteurization, GIS, Agricultural and Food Policy, Food Consumption/Nutrition/Food Safety, L510, Q180, Q220,
Karns, Shawn A. +2 more
core +1 more source
Processing strategies. QLIF subproject 5: Development of a framework for the design of minimum and low input processing strategies, that guarantee food quality and safety [PDF]
Organic processing standards already prohibit the use of many chemicals, additives and preservatives, which are used in the processing of conventional foods.
Kretzschmar, U.
core
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Metabolomics analysis reveals the bitter active ingredients in Lonicera caerulea L.
IntroductionBlue honeysuckle (Lonicera caerulea L.) is a nutritionally valuable cold-climate berry characterized by a considerable bitter taste. While bitter compounds in plant foods are often associated with favorable physiological activities, their ...
Ling Zhu +17 more
doaj +1 more source
This scientific opinion of EFSA deals with the risk assessment of the additive 1,2‐benzisothiazol‐3(2H)‐one 1,1‐dioxide, sodium salt (saccharin, sodium salt), with CAS No 128‐44‐9 and FCM Substance No 902, for use as a nucleating agent up to 0.1% w/w in ...
EFSA Panel on food contact materials, enzymes, flavourings and processing aids (CEF)
doaj +1 more source
One of the basic problems in local organic food systems seems to be connected to food chains. The range of creative initiatives covers all thinkable fields: information about ecology, farmers' own activities in creating brands and labels, associations ...
Kakriainen, Salla, von Essen, Hans
core
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to evaluate 50 flavouring substances in the Flavouring Group Evaluation 6, Revision 3, using the Procedure in Commission ...
EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF)
doaj +1 more source

