Results 71 to 80 of about 14,427,413 (359)

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Method for the validation and uncertainty estimation of tocopherol analysis applied to soybean oil with addition of spices and TBHQ

open access: yesGrasas y Aceites, 2013
The tocopherol contents of refined soybean oil with the addition of rosemary, oregano, garlic, annatto seeds and TBHQ was evaluated during storage at 25 °C and 35 °C for twelve months, in comparison with a control soybean oil without the antioxidant ...
M. G. da Silva   +5 more
doaj   +1 more source

Quality related communication approaches for organic food [PDF]

open access: yes
As food quality becomes more complex, consumer s are tending to reduce their involvement in the food purchase decision- making process. Consequently, prices are becoming more significant as they represent an easy choice criterion when consumer s have ...
Bodini, Antonella   +2 more
core   +1 more source

How to improve customer service at Muffin Break [PDF]

open access: yes, 2018
The research evaluates the ways to improve customer service quality that could have a significant impact on customer satisfaction and customer loyalty in terms of customer service at Muffin Break.
Loona, Sandeep, Yeung, Deniss
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Fermentation process of mulberry juice-whey based Tibetan kefir beverage production

open access: yesCzech Journal of Food Sciences, 2018
Mixture of mulberry juice and whey was evaluated as a potential substrate for the production of a beverage by Tibetan kefir grains. Different mulberry juice addition was used.
Bo LI, Xin GAO, Na LI, Jun MEI
doaj   +1 more source

Bioprotective Culture: A New Generation of Food Additives for the Preservation of Food Quality and Safety

open access: yesIndustrial Biotechnology, 2019
Ensuring food quality and safety will remain a major challenge for the agri-food sector, due in large part to expected limits on the use of conventional microbiological barriers.
L. Ben Said   +4 more
semanticscholar   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

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