Results 41 to 50 of about 2,322,629 (301)

Real‐World Pediatric Blinatumomab Administration: Access to Outpatient Care Delivery and Impact of a Hospital‐Dispensed Model

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Blinatumomab has been shown to be highly effective for patients with pediatric B‐ALL and has recently become standard of care therapy. Due to its past use in the clinical trial setting, there is limited information available about real‐world administration.
Katelyn Oranges, Kelly A. Duffy, Sara McDonough, Evelyn Kurpiewski, R. Jennifer Randall, Allison Barz Leahy, Haley M. Newman, Joyce P. Lee, Stephen P. Hunger, Anne F. Reilly, David T. Teachey, Susan R. Rheingold, Daniel J. Zheng   +12 more
wiley   +1 more source

Reasoned opinion on the modification of the existing MRLs for isopyrazam in pome fruits, various stone fruits and oilseeds [PDF]

, 2013
In accordance with Article 6 of Regulation (EC) No 396/2005, the United Kingdom, hereafter referred to as the evaluating Member State (EMS), received an application from Syngenta Crop Protection UK Ltd to modify the existing MRLs for the active substance
European Food Safety Authority
core   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance flurochloridone [PDF]

EFSA Journal, 2013
The conclusions of the European Food Safety Authority (EFSA) following the peer review of the initial risk assessment carried out by the competent authority of the rapporteur Member State Spain, for the pesticide active substance flurochloridone are ...
European Food Safety Authority
doaj   +1 more source

Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance lenacil [PDF]

, 2013
The conclusions of the European Food Safety Authority (EFSA) following the peer review of an initial risk assessment carried out by the competent authority of the rapporteur Member State Belgium, relating to the pesticide active substance lenacil are ...
European Food Safety Authority
core   +1 more source

Prevalence and Trajectory of Household Material Hardship Among Children With Advanced Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Families of children with advanced cancer living in poverty experience inferior outcomes including poor parent mental health and worse child quality of life. Household material hardship (HMH: food, housing, transportation, and/or utility insecurity) is a modifiable poverty exposure—and potential intervention target—that ...
Sarah Wright, Morgan A. Paul, Selena Murcia Mendez, Emily Jones, Lucille Lokko, Chelsea Heneghan, Nicholas Purol, Morgan Arnold, Rahela Aziz‐Bose, Colleen A. Kelly, Sandi L. Pruitt, Joanne Wolfe, Kira Bona, Puja J. Umaretiya   +13 more
wiley   +1 more source

Statement of EFSA on host plants, entry and spread pathways and risk reduction options for Xylella fastidiosa Wells et al.

EFSA Journal, 2013
Following a request from the European Commission, EFSA was asked to provide urgent scientific and technical assistance on the plant pathogenic bacterium Xylella fastidiosa. X.
European Food Safety Authority
doaj   +1 more source

Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione [PDF]

EFSA Journal, 2013
The conclusions of the European Food Safety Authority (EFSA) following the peer review of the initial risk assessments carried out by the competent authority of the rapporteur Member State Austria, for the pesticide active substance tembotrione are ...
European Food Safety Authority
doaj   +1 more source

Reasoned opinion on the modification of the existing MRL for iprodione in celeriac [PDF]

, 2012
<p>In accordance with Article 6 of Regulation (EC) No 396/2005, Belgium, hereafter referred to as the evaluating Member State, compiled an application to modify the existing MRL for the active substance iprodione in celeriac.
European Food Safety Authority
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source