Results 211 to 220 of about 1,184,955 (290)

A Qualitative Analysis of Patient Perspectives and Preferences in Lupus Management to Guide Lupus Guidelines Development

open access: yesArthritis Care &Research, EarlyView.
Objective A patient‐centered approach for chronic disease management, including systemic lupus erythematosus (SLE), aligns treatment with patients’ values and preferences, leading to improved outcomes. This paper summarizes how patient experiences, perspectives, and priorities informed the American College of Rheumatology (ACR) 2024 Lupus Nephritis (LN)
Shivani Garg   +20 more
wiley   +1 more source

Clinical Practice Guideline for Evaluation and Management of Peripheral Nervous System Manifestations in Sjögren's Disease

open access: yesArthritis Care &Research, Accepted Article.
Objectives Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies. To help patients and providers in the decision‐making process, we developed
Anahita Deboo   +19 more
wiley   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

open access: yesAdvanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio   +11 more
wiley   +1 more source

Functional Integration of Different‐Sex Gonad Transplants Into the Adult Mouse Hypothalamic Pituitary Gonadal Axis

open access: yesAdvanced Biology, EarlyView.
This study introduces and investigates different‐sex gonad transplants in a mouse model of gender‐affirming hormone therapy. Ovaries and testes implanted into gonadectomized adults exhibit gametogenesis and steroidogenesis independent of the sex of the host.
Daniel R. Pfau   +8 more
wiley   +1 more source

Analytical Chemistry in Food Science

open access: diamond, 1997
Renato Amadò   +2 more
openalex   +2 more sources

Synergistic Roles of FAHD‐1 and PYC‐1 in Mitochondrial Function, Behavior, and Longevity in C. elegans

open access: yesAdvanced Biology, EarlyView.
FAHD‐1 and PYC‐1 catalyze opposing mitochondrial reactions that regulate oxaloacetate homeostasis in Caenorhabditis elegans. Using single and double knockouts, this study reveals that both enzymes shape locomotion, reproduction, respiration, and lifespan.
Riccardo Giaquinta   +3 more
wiley   +1 more source

Geometric Optimization and Mechanical Performance Enhancement of Auxetic Structures for High‐Impact Applications Through Fused Deposition Modeling

open access: yesAdvanced Engineering Materials, EarlyView.
This study explores the mechanical performance of three auxetic structures, identifying a re‐entrant‐star hybrid as the most effective for impact absorption. Finite element simulations and experiments demonstrate significant gains in energy absorption and flexural strength after geometric optimization. This study investigates the mechanical performance
Malik Hassan   +4 more
wiley   +1 more source

Composite Electrospun Fibers Containing Optimized B‐ and Cu‐Doped Bioactive Glass Sol‐Gel Particles for Potential Soft Tissue Engineering Applications

open access: yesAdvanced Engineering Materials, EarlyView.
This article describes the preparation and characterization of poly(ε‐caprolactone) electrospun composite fibers incorporating sol‐gel‐derived bioactive glass particles doped with B and Cu. Scanning electron microscopy, energy‐dispersive X‐ray spectroscopy, Fourier‐transform infrared spectroscopy, contact angle, acellular bioactivity, mechanical and ...
Elisa Piatti   +5 more
wiley   +1 more source

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