Results 91 to 100 of about 541,246 (311)

Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology

Advanced Science, EarlyView.
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto, Tristan Dellazizzo Toth, Silvano Bond, Alexander Schmitz, Rim Diab, Sara Y. Ngo Tenlep, Brian Mooney, Silvia Erni, Martina Schobesberger, Olivier Scheidegger, Camille Peitsch, Smita Saxena   +11 more
wiley   +1 more source

Tackling Household Food Insecurity: The Experience of Vietnam [PDF]

This paper is a systematic review of the facts and figures related to the issues of food security in Vietnam. Based on a comprehensive definition of food security as “access by all people at all times to enough, nutritionally adequate, and safe food ...
Britta Ogle, Kjell Havnevik, Linley Chiwona-Karltun, Trang Thi Huy Nhat   +3 more
core  

PRDM1+ Malignant Cells Mediate an Immunosuppressive Landscape and Resistance to Neoadjuvant Chemoradiotherapy and Immunotherapy in Esophageal Squamous Cell Carcinoma

Advanced Science, EarlyView.
Integrated scRNA‐seq, scTCR‐seq analysis, and functional assays identify PRDM1+ malignant epithelial cells with hyper lipid peroxidation characteristics that demonstrate reduced responsiveness to the nICRT treatment. Principal factor PRDM1 activates cysteine metabolism genes to modulate lipid peroxidation (an intrinsic cellular pathway related to ...
Dijian Shen, Rui Li, Yong She, Xuefei Liu, Yuanyang Huang, Yongling Ji, Keying Chen, Zhengbo Song, Runzhe Chen, Xuan Li, Qi Zhao, Qixun Chen, Ming Chen   +12 more
wiley   +1 more source

Impact of public climate change adaptation policies on women's employment and poverty in Burkina Faso

World Development Sustainability
Climate change is expected to bring hotter periods and reduced rainfall to Burkina Faso, decreasing water availability and soil moisture. This will negatively affect agriculture and food production.
Boureima Sawadogo
doaj   +1 more source

Smallholder Cash Cropping, Food Cropping, and Food Security in Northern Mozambique: Research Methods [PDF]

Ministry of Agriculture and Rural Development, Directorate of Economics, Republic of Mozambiquefood security, food policy, Mozambique, cash cropping, food cropping, Crop Production/Industries, Food Security and Poverty, Q18,
Anonymous
core   +1 more source

High‐Fidelity Synthetic Data Replicates Clinical Prediction Performance in a Million‐Patient Diabetes Cohort

Advanced Science, EarlyView.
This study generates high‐fidelity synthetic longitudinal records for a million‐patient diabetes cohort, successfully replicating clinical predictive performance. However, deeper analysis reveals algorithmic biases and trajectory inconsistencies that escape standard quality metrics. These findings challenge current validation norms, demonstrating why a
Francisco Ortuño, Víctor M. de la Oliva Roque, Javier‐Ignacio Ramirez‐Lopez, David P. Kreil, Joaquín Dopazo, Carlos Loucera   +5 more
wiley   +1 more source

Review of Challenges Experienced by Women in Subsistence Crop Production

Indonesian Journal of Social and Environmental Issues
Men and women are assigned roles and obligations that they must fulfill to sustain the welfare of their households. These are adhered to despite the challenges encountered by women, essential food producers within households, to guarantee sustainable ...
Sejabaledi Agnes Rankoana
doaj   +1 more source

Some Characteristics of Pro-poor Growth, and Policy Implications for Mozambique [PDF]

Resultados das investigações do Departamento de Análise de Políticas MADER-Direcção de Economíafood security, food policy, Mozambique, pro-poor growth, poverty reduction, Agricultural and Food Policy, Food Security and Poverty, Q18,
Tschirley, David L.
core   +1 more source

An Increasing Misalignment Between Crop Distribution and Environmental Resources Under Climate Change in China

Advanced Science, EarlyView.
Climate change reshapes the spatial alignment between crop production and environmental resources. Using multi‐source data and a crop model, integrated climatic, water, and soil endowments for maize and wheat are quantified and compared with harvest distributions.
Zheng'e Su, Zhentao Zhang, Jin Zhao, Xia Liang, Chuang Zhao, Zhijuan Liu, Minghao Zhuang, Jing Sun, Bo Lu, Ke Liu, Johannes W. M. Pullens, Matthew T. Harrison, Deli Chen, Xiaoguang Yang   +13 more
wiley   +1 more source

Linking urban food security, urban food systems, poverty, and urbanisation

, 2018
The majority of research on food security and food poverty conducted in Africa focuses its attention solely at the household scale. This chapter argues that this has led to a series of inappropriate policies and programmes that neglect the systemic drivers of food insecurity.
Jane Battersby, Gareth Haysom
openaire   +1 more source