Results 51 to 60 of about 7,213,555 (296)

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Impact of the world agricultural grocery markets on self-development of regional agrarian systems [PDF]

Экономика региона, 2011
This paper analyzes the impact of foreign economic grocery relations on the state of self-development and self-regulation in the agrarian sector of the country and regions.
Veniamin Vasil'evich Drokin, Aleksey Serafimovich Zhuravlev, Yuriy Fedorovich Chistyakov   +2 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Analysis of the self-sufficiency of wheat production in Bosnia and Herzegovina [PDF]

Bulletin of Natural Sciences Research
Wheat is recognized as a crucial staple food across nearly all countries. Achieving a specific level of self-sufficiency in primary food products is a common objective for nations, aimed at safeguarding domestic production, minimizing dependency on ...
Ivanišević Marko, Popov Tatjana, Gvozden-Sliško Dijana   +2 more
doaj   +1 more source

ASYMMETRY OF SELF-SUFFICIENCY IN POTATO PRODUCTION IN THE EUROPEAN UNION [PDF]

Annals of the Polish Association of Agricultural and Agribusiness Economists, 2018
Potato cultivation has been recognized for many years as the basic source of food for the population onall continents. The purpose of the article was to attempt to assess the self-sufficiency of potato productionin EU countries as a product of great ...
Krzysztof Firlej, Sebastian Kubala
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Multi-objective optimization identifies trade-offs between self-sufficiency and environmental impacts of regional agriculture in Baden-Württemberg, Germany

Journal of Agriculture, Food Systems, and Community Development, 2020
Regional food supply, organic farming, and chang­ing food consumption are three major strategies to reduce the environmental impacts of the agricul­tural sector.
Christian Buschbeck, Larissa Bitterich, Christian Hauenstein, Stefan Pauliuk   +3 more
doaj   +1 more source

Food security and self-sufficiency in food: methodological aspects

Market economy problems, 2021
The purpose of this article is to consider the concept of food security both from the view of households and agricultural producers, estimation of the relationship between the main components of food security and economic policy, analyze the impact of foreign economic policy instruments and the external environment on the level of food independence ...
openaire   +1 more source

Historical trends of food self-sufficiency in Africa [PDF]

Food Security, 2013
The majority of African countries are stricken by food shortages and undernourishment, with much of the population lacking reliable access to food supplies and basic dietary requirements. In this paper, we analyze past trends of food production and consumption in Africa, both for the continent as a whole and for 52 individual countries within it ...
Luan, Yibo, Cui, Xuefeng, Ferrat, Marion
openaire   +1 more source