Results 91 to 100 of about 5,347,238 (307)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Real-time food intake classification and energy expenditure estimation on a mobile device [PDF]

open access: yes, 2015
© 2015 IEEE.Assessment of food intake has a wide range of applications in public health and life-style related chronic disease management. In this paper, we propose a real-time food recognition platform combined with daily activity and energy expenditure
Lo, B, Ravi, D, Yang, G
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

The pilot food price subsidy scheme in the Philippines: its impact on income, food consumption, and nutritional status [PDF]

open access: yes
Food relief Philippines Case studies., Food consumption Philippines Case studies., Nutrition Philippines Case studies.,
Garcia, Marito, Pinstrup-Andersen, Per
core  

A Synthesis of the Literature on the Relationship Between Food Access and Overweight and Obesity in African American Adolescents [PDF]

open access: yes, 2013
Food access shapes a community’s nutritional environment and impacts the health and physical well-being of its residents. When a community does not have adequate access to outlets that offer healthy options, it is difficult to maintain a healthy diet ...
Smalls, Marquita Noelle Bullock
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Molecular targets of omega 3 and conjugated linoleic fatty acids – micromanaging cellular response

open access: yesFrontiers in Physiology, 2012
Essential fatty acids cannot be synthesized de novo by mammals and need to be ingested either with the diet or through the use of supplements/functional foods to ameliorate cardiovascular prognosis.
Francesco eVisioli   +3 more
doaj   +1 more source

Leading by example: A three-wave sequential mixed method food safety study [PDF]

open access: yes, 2019
(Best Paper Award/ 253 submissions) According to the most recent government data, approximately 61% of foodborne illness outbreaks were attributed to lack of personal hygiene and improper food handling by employees in the foodservice industry ...
Lin, Naiqing, Paez, Paola
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Canadian Food Studies evolves

open access: yesCanadian Food Studies, 2019
no ...
Ellen Desjardins, Wesley Tourangeau
doaj   +1 more source

Home - About - Disclaimer - Privacy