Results 31 to 40 of about 250,155 (310)

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Allochthonous resources are less important for faunal communities on highly productive, small tropical islands

Ecology and Evolution, 2021
Ecosystems are interconnected by energy fluxes that provide resources for the inhabiting organisms along the transition zone. Especially where in situ resources are scarce, ecosystems can become highly dependent on external resources.
Sebastian Steibl, Robert Sigl, Sanja Blaha, Sophia Drescher, Gerhard Gebauer, Elif Gürkal, Frederic Hüftlein, Anna Satzger, Michael Schwarzer, Dimitri Seidenath, Jana Welfenbach, Raphael S. Zinser, Christian Laforsch   +12 more
doaj   +1 more source

Investigating food web structure and system function of an artificial reef ecosystem based on carbon and nitrogen stable isotope analysis: implications for reef management

Frontiers in Marine Science, 2023
IntroductionFood web is an important basis for identifying trophodynamic processes, and evaluating the structural and functional characteristics of ecosystems.
Jie Feng, Jie Feng, Jie Feng, Jie Feng, Jie Feng, Jie Feng, Xiaolong Zhao, Fan Bi, Fan Bi, Wei Zhao, Wei Zhao, Wei Zhao, Wei Zhao, Liang Zhao, Liang Zhao, Liang Zhao, Liang Zhao, Hao Song, Hao Song, Hao Song, Hao Song, Meijie Yang, Meijie Yang, Meijie Yang, Meijie Yang, Zhi Hu, Zhi Hu, Zhi Hu, Zhi Hu, Cong Zhou, Cong Zhou, Cong Zhou, Cong Zhou, Pu Shi, Pu Shi, Pu Shi, Pu Shi, Pengpeng Hu, Pengpeng Hu, Pengpeng Hu, Pengpeng Hu, Peizhen Ma, Pengfei Sun, Han Jiang, Jiangling Xu, Jiangling Xu, Tao Zhang, Tao Zhang, Tao Zhang, Tao Zhang   +49 more
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Metabarcoding and morphological analysis of diets of mesopelagic fishes in the NW Atlantic Slope Water

Frontiers in Marine Science
DNA metabarcoding and morphological taxonomic (microscopic) analysis of the gut contents was used to examine diet diversity of seven species of fishes collected from mesopelagic depths (200-1000 m) in the NW Atlantic Ocean Slope Water during Summer 2018 ...
Ann Bucklin, Paola G. Batta-Lona, Jennifer M. Questel, Helena McMonagle, Helena McMonagle, Melissa Wojcicki, Joel K. Llopiz, Sarah Glancy, Paul E. Caiger, Paul E. Caiger, Rene Francolini, Annette Govindarajan, Simon R. Thorrold, Michael Jech, Peter H. Wiebe   +14 more
doaj   +1 more source

The plankton and the marine food web

, 2021
10 figuresHere, I will post few drawings of plankton and their role in the marine food web. All drawings and pictures belong to me, Albert Calbet. If you want to use any for teaching or non-comercial use let me know.
Calbet, Albert
core  

CAR T‐Cell Therapy in Neurology: A Scoping Review of Neuro‐Oncology, Autoimmune Diseases & Neurotoxicity

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi, Mohammed Dibas, Patricia Tai, Ala Dibas, Osama Souied, Suhair Al‐Ghabeesh   +5 more
wiley   +1 more source

Immunosuppressive Drug Use in Limited Systemic Sclerosis: An International Survey

Arthritis Care &Research, EarlyView.
Objective Current guidelines recommend immunosuppressive treatment for diffuse cutaneous systemic sclerosis but are less clear on their use in limited cutaneous systemic sclerosis (lcSSc) in the absence of internal organ complications. We conducted an international survey to understand current immunosuppressive drug prescribing patterns in lcSSc ...
Sabrina Hoa, Yicheng Mu, Marie Hudson, Janet Pope   +3 more
wiley   +1 more source

Food and You Survey, 2010

, 2011
copyright UK Data Service and data collection copyright owner.The Food and You Surveys (2010-2018), and Food and You 2 (2020- ) are bi-annual, cross-sectional surveys of adults aged 16 years and over living in England, Wales and Northern Ireland,  ...
Food Standards Agency, TNS-BMRB
core   +1 more source

Zein‐Based Adhesives: Sustainable Extraction and Application in Bioadhesive Technologies

Advanced Engineering Materials, EarlyView.
Zein is extracted from corn gluten meal using a simple and scalable process with high yield (~90%). The resulting protein is applied in bioadhesives modified with Ca2+ and Fe3+ ions, exhibiting substrate‐dependent adhesion. The findings demonstrate competitive bonding performance and highlight the role of ionic interactions in tuning adhesion ...
Paula Bertolino Sanvezzo, Daniela Winsley Valereto Friozi, Vinícius de Oliveira, Marcia Cristina Branciforti   +3 more
wiley   +1 more source