Results 161 to 170 of about 214,010 (272)

Effects of Selective Sphingosine‐1‐Phosphate Receptor 1 Agonist, TRV045, on Evoked Pain Tests: An Exploratory, Four‐Way Cross‐Over Study in Healthy Volunteers

European Journal of Pain, Volume 30, Issue 6, July 2026.
ABSTRACT Introduction Preclinical evidence suggests that dysregulation of the ceramide‐sphingosine‐1‐phosphate (S1P) axis may have analgesic properties. However, currently approved S1PR1 modulators such as fingolimod are hindered for this indication as they induce lymphopenia.
Wouter A. Bakker, P. Eijsvogel, Erica S. Klaassen, Jessica Kim, Ruihua Chen, Mark A. Demitrack, Albert Dahan, Marieke Niesters, Hemme J. Hijma, Geert Jan Groeneveld   +9 more
wiley   +1 more source

Absence of a dose-response relationship after intra-oropharyngeal inoculation of pigs with foot-and-mouth disease virus serotype O. [PDF]

Vet Res
Wisnewski K, Lorenz C, Weber S, Schmidt S, Waters R, Eblé P, Dekker A, Gerner W, Eschbaumer M.   +8 more
europepmc   +2 more sources

Immune Dysregulation in Branched Chain Organic Acidemias

Journal of Inherited Metabolic Disease, Volume 49, Issue 4, July 2026.
ABSTRACT Organic acidemias (OAs) are a group of inherited disorders, most commonly caused by defects in mitochondrial enzymes involved in amino acid and fatty acid metabolism. While they characteristically present with metabolic and neurological crises, growing evidence reveals a significant burden of chronic immune dysregulation in some disorders and ...
Abdul L. Shakerdi, Jack Drda, Justin A. Dutta, Jerry Vockley   +3 more
wiley   +1 more source

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

Medicinal Research Reviews, Volume 46, Issue 4, Page 1173-1229, July 2026.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur, Mandeep Rana, Sakshi Vanjani, Kei‐Chi Liou, Rajeev Taliyan, Kunal Nepali, Chih‐Hao Yang   +6 more
wiley   +1 more source

Mechanistic role of lipid metabolism in foot-and-mouth disease virus (FMDV) replication. [PDF]

Vet Res
Zhang Y, Meng F, Li L, Liu G, Tian Q, Liu Y, Li T, Gu L, Gong J, Liu C, Wen X, Wan F, Xiao H, Liu Y, Wang S, Cao J.   +15 more
europepmc   +1 more source

Structure of Foot-and-Mouth Disease Virus

, 1990
Acharya, R, Fry, E, Logan, D, Stuart, D, Fox, G, Rowlands, D, Brown, F   +6 more
openaire   +2 more sources

Serotype Characterization and Transmission Modelling of Foot‐and‐Mouth Disease in Dairy Farms, Bishoftu, Ethiopia

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
FMD outbreaks in dairy farms in Bishoftu were characterized by rapid within‐farm transmission (R0 = 3.7) and predominance of the SAT‐2 serotype. Current trivalent vaccination alone was insufficient for control, highlighting the need for improved vaccine matching and strengthened biosecurity measures . ABSTRACT Background Foot‐and‐mouth disease (FMD) is
Eyerusalem Fetene, Dereje Shegu, Ayelech Muluneh, Abde Aliy, Jan Paeshuyse, Fanos Tadesse Woldemariyam, Haileleul Negussie, Samson Leta   +7 more
wiley   +1 more source

Foot-and-mouth disease virus infection of sheep: implications for diagnosis and control

, 2002
Foot-and-mouth disease virus infection of sheep: implications for diagnosis and ...
AI Donaldson (14869999), MEJ Woolhouse (14869996), V Mioulet (13676260), RP Kitching (14869981), GJ Hughes (14869993), Soren Alexandersen (13095615)   +5 more
core  

First Serological Evidence of Foot‐and‐Mouth Disease Virus (FMDV) Infection Among Sheep and Goats in Selected Districts of Central Bangladesh

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
Serological surveillance revealed foot‐and‐mouth disease virus (FMDV) exposure for the first time in sheep and goats across the studied districts of Bangladesh, highlighting their critical role in FMD epidemiology. These findings emphasize the importance of including sheep and goats in national FMD surveillance and control programmes.
Tahmina Sikder, Md. Jisan Ahmed, Basant Saud, Tasmiah Tarin, Md. Imran Hossain, Anowar Hossen, Mohammed Abdus Samad, Mohammad Rafiqul Islam, Munazah Shahzad, Nadeem Shabir, Won‐Il Kim, Amina Khatun   +11 more
wiley   +1 more source

Immunohistochemical Detection of Foot-and-Mouth Disease Virus in Carrier African Buffalo (Syncerus caffer). [PDF]

Vet Med Sci
Henning A, Quan M, Loots A, Odendaal L.
europepmc   +1 more source