Results 81 to 90 of about 4,418,098 (306)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Deception mechanisms of FDA‒AWACS against passive monopulse angle measurements

IET Radar, Sonar & Navigation
Airborne warning and control systems (AWACS) serve as critical command and control centres in air combat operations, making them prime targets for strategic attacks.
Bo Wang, Gang Wang, Yonglin Li, Rennong Yang, Yu Zhao   +4 more
doaj   +1 more source

Force control in chronic stroke

Neuroscience & Biobehavioral Reviews, 2015
Force control deficits are common dysfunctions after a stroke. This review concentrates on various force control variables associated with motor impairments and suggests new approaches to quantifying force control production and modulation. Moreover, related neurophysiological mechanisms were addressed to determine variables that affect force control ...
Nyeonju, Kang, Kang, Nyeonju, Cauraugh, James H.   +2 more
openaire   +3 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Accurate semi‐direct lidar‐inertial odometry based on distance and normal direction

Electronics Letters
To improve the autonomous navigation capability of unmanned platforms, an accurate semi‐direct lidar‐inertial odometry algorithm with a new point cloud alignment evaluation metric is proposed.
Erliang Yao, Haitao Song, Jing Zhao
doaj   +1 more source

A Multi-Fidelity Data Fusion Approach Based on Semi-Supervised Learning for Image Super-Resolution in Data-Scarce Scenarios

Sensors
Image super-resolution (SR) techniques can significantly enhance visual quality and information density. However, existing methods often rely on large amounts of paired low- and high-resolution (LR-HR) data, which limits their generalization and ...
Hongzheng Zhu, Yingjuan Zhao, Ximing Qiao, Jinshuo Zhang, Jingnan Ma, Sheng Tong   +5 more
doaj   +1 more source

Inverted Pendulum Human Transporter Balance Control System Based on Proportional Integral Derivative – Active Force Control [PDF]

, 2011
Many research for the balancing of inverted pendulum control system to develop the performance. This paper will simulate a Proportional Integral Derivative – Active Force Control (PID-ACF) methods to swing a pendulum attached to a cart from an initial ...
Pitowarno, Endra, putra, kamajaya
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Research on methods to enhance the survivability of AWACS with FDA against anti‐ARMs on a battlefield

IET Microwaves, Antennas & Propagation
The Airborne Warning and Control System (AWACS) are pivotal assets in aerial operations, necessitating specialised protection measures, and serving as prime targets for enemy anti‐radiation missiles (ARMs).
Bo Wang, Gang Wang, Rengnong Yang, Yonglin Li, Yu Zhao   +4 more
doaj   +1 more source

An Unsupervised Situation Awareness Framework for UAV Sensor Data Fusion Enabled by a Stabilized Deep Variational Autoencoder

Sensors
Effective situation awareness relies on the robust processing of high-dimensional data streams generated by onboard sensors. However, the application of deep generative models to extract features from complex UAV sensor data (e.g., GPS, IMU, and radar ...
Anxin Guo, Zhenxing Zhang, Rennong Yang, Ying Zhang, Liping Hu, Leyan Li   +5 more
doaj   +1 more source